Genetic evidence for two founding populations of the Americas
View abstract on PubMed
Summary
This summary is machine-generated.Genetic research reveals some Amazonian Native Americans have ancestry linked to Australasians, suggesting diverse founding populations in the Americas beyond previous understanding.
Area Of Science
- Population Genetics
- Human Origins
- Ancient DNA Analysis
Background
- Previous genetic studies suggested a single origin for Native Americans from Northeast Asia.
- Morphological studies indicated some early American skeletons shared traits with Australasians, contrasting with Northeast Asian affinities.
- This suggested a potentially more complex peopling of the Americas than previously accepted.
Purpose Of The Study
- To investigate the ancestral origins of Native American populations using genome-wide data.
- To clarify the genetic relationships between ancient and present-day Native Americans and other global populations.
- To assess the diversity of founding populations in the Americas.
Main Methods
- Analysis of genome-wide data from present-day Amazonian Native Americans.
- Comparison of genetic signatures with various global populations, including indigenous Australians, New Guineans, Andaman Islanders, Eurasians, and ancient North American genomes.
- Investigated genetic admixture and ancestral components.
Main Results
- Identified a Native American founding population in some Amazonian groups with ancestry more closely related to indigenous Australians, New Guineans, and Andaman Islanders than to present-day Eurasians or Native Americans.
- This distinct ancestral signature was largely absent in present-day Northern and Central Americans.
- The signature was also not detected in a ~12,600-year-old Clovis-associated genome.
Conclusions
- The findings suggest a more diverse set of founding populations for the Americas than previously accepted.
- Supports the hypothesis of multiple ancestral lineages contributing to the peopling of South America.
- Highlights the importance of ancient DNA and genomic data in resolving complex human migration histories.

