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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

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Risk of mortality in relation to an updated classification of left ventricular geometric abnormalities in a general

Cesare Cuspidi1, Rita Facchetti, Michele Bombelli

  • 1aDepartment of Health Science, University of Milano-Bicocca bIstituto Auxologico Italiano IRCCS cDepartment of Clinical Sciences and Community Health University of Milano and Fondazione Ospedale Maggiore Policlinico, Milan, Italy dUniversity Clinical Hospital Centre 'Dragisa Misovic', Belgrade, Serbia eIRCCS Multimedica, Sesto San Giovanni, Milan, Italy.

Journal of Hypertension
|July 22, 2015
PubMed

Insights

Left ventricular hypertrophy patterns, particularly concentric LVH, significantly increase cardiovascular and all-cause mortality risk. This new classification system aids in better risk stratification for the general population.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Clinical Epidemiology

Background:

  • Left ventricular geometry is crucial for cardiovascular health.
  • Existing classification systems may not fully capture mortality risk.
  • A new classification system from the Dallas Heart Study offers potential improvements.

Purpose of the Study:

  • To evaluate the association between left ventricular geometric patterns, using a new classification system, and mortality risk.
  • To assess cardiovascular and all-cause mortality in a general population sample.
  • To determine if the new classification system improves risk stratification.

Main Methods:

  • Utilized data from 1716 participants in the Pressioni Monitorate e Loro Associazioni (PAMELA) study.
  • Defined abnormal left ventricular geometric patterns based on left ventricular mass index, diameter, and relative wall thickness.
  • Followed participants for an average of 211 months, collecting death certificate data.

Main Results:

  • Concentric left ventricular hypertrophy (LVH) was associated with a 2.20-fold increased risk of cardiovascular mortality.
  • Eccentric dilated LVH and eccentric nondilated LVH also predicted increased cardiovascular and all-cause mortality.
  • Concentric LVH remained a significant predictor of mortality even after adjusting for left ventricular mass index.

Conclusions:

  • The new classification system for left ventricular geometric patterns enhances mortality risk stratification in the general population.
  • Risk is strongly linked to left ventricular mass, with concentric LVH providing unique prognostic information.
  • This classification system may be valuable for identifying individuals at higher risk of mortality.
Abstract

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