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The Role of Exercise-Induced Cardiovascular Adaptation in Brain Health
11Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas; and 2Departments of Internal Medicine and 3Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX.
Abstract:
Regular aerobic exercise improves brain health; however, a potential dose-response relationship and the underling physiological mechanisms remain unclear. Existing data support the following hypotheses: 1) exercise-induced cardiovascular adaptation plays an important role in improving brain perfusion, structure, and function, and 2) a hormetic relation seems to exist between the intensity of exercise and brain health, which needs to be further elucidated.
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