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Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
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In Response

Ting Ding1, Dong-Xin Wang

  • 1Department of Anesthesiology and Surgical Intensive Care, Peking University First Hospital, Beijing, China, wangdongxin@hotmail.com.

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