Related Experiment Video
Updated: Apr 6, 2026
08:55
The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia
Published on: November 30, 2016
17.4K
[Cancer and Malnutrition].
Norimasa Tsuzuki1, Takashi Higashiguchi, Akihiro Ito
1Dept. of Surgery and Palliative Medicine, Fujita Health University, School of Medicine.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|July 23, 2015
Summary
Nutrition support is crucial for cancer patients to prevent malnutrition and improve treatment tolerance. For terminally ill patients with refractory cachexia, a "gear-change" in nutrition may be necessary to reduce burden and maintain bodily function.
Area of Science:
- Oncology
- Nutrition Science
- Metabolism
Context:
- The precise, quantitative relationship between nutrition and a healthy life remains unclear.
- Cancer cachexia, a severe malnutrition state in cancer patients, necessitates careful management.
- Current understanding highlights the benefits of nutrition support in mitigating malnutrition and enhancing therapy tolerance.
Purpose:
- To explore the role of nutrition support in managing cancer cachexia.
- To define the concept of
- gear-change
- in nutrition for refractory cachexia.
- To establish guidelines for adjusting nutrition support in advanced cancer.
Summary:
- Nutrition support is vital for cancer patients, preventing malnutrition and improving tolerance to anticancer therapies.
- In refractory cachexia, a reduction in nutrition support (a "gear-change") may be required as it can burden the body.
- This approach involves restricting nutritional intake while focusing on medical treatments to preserve bodily function.
Impact:
- Optimizing nutrition management for cancer patients, particularly those with refractory cachexia.
- Improving quality of life for terminally ill cancer patients.
- Reducing the physiological burden of nutrition support in end-of-life care.
Related Concept Videos
01:19Psychoneuroimmunology: Diabetes and Cancer
636
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
636
02:53Adaptive Mechanisms in Cancer Cells
7.4K
Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
7.4K
02:53Adaptive Mechanisms in Cancer Cells
4.3K
4.3K
02:59Cancer Prevention
8.7K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
8.7K
02:59Cancer Prevention
3.0K
3.0K
02:18Cancer
55.9K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
55.9K