Quinolizidine derivatives as potential antitumoral agents

Hydrogen sulphide-releasing diclofenac derivatives inhibit breast cancer-induced osteoclastogenesis in vitro and prevent osteolysis ex vivo.

British journal of pharmacology·2011

H2S releasing aspirin protects amyloid beta induced cell toxicity in BV-2 microglial cells.

Neuroscience·2011

Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease.

European journal of medicinal chemistry·2011

Dithiolethione compounds inhibit Akt signaling in human breast and lung cancer cells by increasing PP2A activity.

Oncogene·2009

Targeting the plasmepsin 4 orthologs of Plasmodium sp. with "double drug" inhibitors.

Protein and peptide letters·2008

H2S-donating sildenafil (ACS6) inhibits superoxide formation and gp91phox expression in arterial endothelial cells: role of protein kinases A and G.

British journal of pharmacology·2008

Chemical and biochemical transformations of 5-ethoxycarbonyl-5-phenyl-2-isoxazolines.

Farmaco (Societa chimica italiana : 1989)·2005

Nasal administration of heparin-loaded microspheres based on poly(lactic acid).

Farmaco (Societa chimica italiana : 1989)·2005

New 8-substituted xanthiene derivatives as potent bronchodilators.

Farmaco (Societa chimica italiana : 1989)·2005

In situ and in vivo efficacy of peroral absorption enhancers in rats and correlation to in vitro mechanistic studies.

Farmaco (Societa chimica italiana : 1989)·2005

Synthesis of 3-aryl-5-decapentyl-1,2,4-oxadiazoles possessing antiinflammatory and antitumor properties.

Farmaco (Societa chimica italiana : 1989)·2005

Syntheses, in vitro antibacterial and antifungal activities of a series of N-alkyl, 1,4-dithiines.

Farmaco (Societa chimica italiana : 1989)·2005

Hepatotoxicity of Avacopan: Real-World Incidence and Confirmed Cases of Severe Drug-Induced Liver Injury in a US National Rheumatology Registry.

Arthritis & rheumatology (Hoboken, N.J.)·2026

Tail-aware heterogeneous graph neural networks for multi-class drug-drug interaction prediction.

Bioinformatics (Oxford, England)·2026

Corrigendum to: Synthesis, Pharmacological Activities, Structure-activity Relationship of 1,3,4-Oxadiazole-Piperazine Conjugates: A Review.

Medicinal chemistry (Shariqah (United Arab Emirates))·2026

Fuzzy Support Vector Regression for QSAR Modeling of 9,10-Dihydrophenanthrene Derivatives Against SARS-CoV-2 3CLpro.

Current computer-aided drug design·2026

Design, Synthesis, In Silico and In Vitro Analysis of Newly Synthesized 2-Mercaptobenzazole Derivatives as Potential Acetylcholinesterase Inhibitors.

Current medicinal chemistry·2026

QSAR Modeling of 1,3,4-Oxadiazole Derivatives for Predicting Anticancer Activity Using SO-PLS Analysis.

Current drug discovery technologies·2026

Related Experiment Videos

Quinolizidine derivatives as potential antitumoral agents

Related Concept Videos

Hydrogen sulphide-releasing diclofenac derivatives inhibit breast cancer-induced osteoclastogenesis in vitro and prevent osteolysis ex vivo.

H2S releasing aspirin protects amyloid beta induced cell toxicity in BV-2 microglial cells.

Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease.

Dithiolethione compounds inhibit Akt signaling in human breast and lung cancer cells by increasing PP2A activity.

Targeting the plasmepsin 4 orthologs of Plasmodium sp. with "double drug" inhibitors.

H2S-donating sildenafil (ACS6) inhibits superoxide formation and gp91phox expression in arterial endothelial cells: role of protein kinases A and G.

Chemical and biochemical transformations of 5-ethoxycarbonyl-5-phenyl-2-isoxazolines.

Nasal administration of heparin-loaded microspheres based on poly(lactic acid).

New 8-substituted xanthiene derivatives as potent bronchodilators.

In situ and in vivo efficacy of peroral absorption enhancers in rats and correlation to in vitro mechanistic studies.

Synthesis of 3-aryl-5-decapentyl-1,2,4-oxadiazoles possessing antiinflammatory and antitumor properties.

Syntheses, in vitro antibacterial and antifungal activities of a series of N-alkyl, 1,4-dithiines.

Hepatotoxicity of Avacopan: Real-World Incidence and Confirmed Cases of Severe Drug-Induced Liver Injury in a US National Rheumatology Registry.

Tail-aware heterogeneous graph neural networks for multi-class drug-drug interaction prediction.

Corrigendum to: Synthesis, Pharmacological Activities, Structure-activity Relationship of 1,3,4-Oxadiazole-Piperazine Conjugates: A Review.

Fuzzy Support Vector Regression for QSAR Modeling of 9,10-Dihydrophenanthrene Derivatives Against SARS-CoV-2 3CLpro.

Design, Synthesis, In Silico and In Vitro Analysis of Newly Synthesized 2-Mercaptobenzazole Derivatives as Potential Acetylcholinesterase Inhibitors.

QSAR Modeling of 1,3,4-Oxadiazole Derivatives for Predicting Anticancer Activity Using SO-PLS Analysis.

Related Experiment Videos

Quinolizidine derivatives as potential antitumoral agents

Abstract:

Related Concept Videos

Related Articles