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Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
Published on: November 6, 2018
Use of a copolymer dressing on superficial and partial-thickness burns in a paediatric population
Insights
This pilot study shows that a copolymer dressing effectively treats partial-thickness burns in children, allowing for shorter hospital stays and high patient satisfaction. The synthetic dressing is easy to apply and manage, reducing pain and infection risk.
Area of Science:
- Burn Care
- Wound Healing
- Biomaterials
Background:
- No single dominant treatment exists for partial-thickness burns.
- Copolymer dressings offer a novel approach to wound management.
Purpose of the Study:
- To evaluate the efficacy and outcomes of copolymer dressing (Suprathel) for superficial and deeper partial-thickness burns in pediatric patients.
- To assess the dressing's impact on hospital stay, pain management, re-epithelialization time, infection rates, and patient/parent satisfaction.
Main Methods:
- A pilot study involving pediatric patients with partial-thickness burns (average 5% total body surface area).
- Copolymer dressing applied as a primary wound dressing after debridement.
- Retrospective evaluation of clinical outcomes and staff experience.
Main Results:
- Average hospital stay was 1.4 days with minimal narcotic use post-application.
- Average re-epithelialization time was 9.5 days with no burn wound infections.
- High patient/parent satisfaction (average 3.66/4) and ease of application reported by staff.
Conclusions:
- Copolymer dressing facilitates early discharge, pain management, and high satisfaction in pediatric burn patients.
- The synthetic dressing is versatile, suitable for deeper burns, donor sites, and contoured areas.
- It simplifies wound care without needing additional antimicrobial coverage.
Objective:
Despite extensive research into the treatment of partial-thickness burns, to date there has not been the emergence of a preeminent modality. This pilot study, the first such study to be performed in a burn unit in the US, was designed to evaluate the efficacy and outcomes of the application of copolymer dressing (Suprathel; PolyMedics Innovations Corporation, Stuttgart, Germany) for both superficial and deeper partial-thickness burns.
Method:
The copolymer dressing was used as a primary wound dressing to treat superficial and deep partial-thickness burns (average 5% total body surface area) in paediatric patients. Burns were debrided within 24 hours, at bedside, in the burn unit or in the operating room. The copolymer dressing was then applied directly to the wound and covered with a non-adherent second layer and an absorptive outer dressing. After discharge, patients were seen every 5-7 days until healed. Parameters evaluated included average hospital length of stay, average number of intravenous doses of narcotics administered, pain score at first follow-up visit, average time to complete re epithelialisation, incidence of burn wound infection, and patient/parent satisfaction on a 4-point scale. We also evaluated our experience with the dressing. Data were evaluated retrospectively under an Investigational Review Board approved protocol.
Results:
Of the 17 patients assessed the average hospital length of stay was 1.4 days during which the average number of intravenous narcotic doses administered before copolymer dressing application was 1.5 and after was 0.1 doses. At the first follow-up visit, average pain score was 1.2 on a 10-point scale and the average time to re epithelialisation was 9.5 days. There was no incidence of burn wound infection. Patient/parent satisfaction was average of 3.66 on a 4-point scale. The staff had found that the self-adherence and elasticity of the dressing made it easy to apply and stay adherent, especially in areas of difficult contour. There were no readmissions for further debridement or skin grafting.
Conclusion:
Our experience shows that patients may be discharged shortly after the application of the copolymer dressing, with manageable pain scores and ease of use as determined by the caretakers high satisfaction. This new, fully synthetic copolymer dressing is easy to apply, does not require any additional antimicrobial coverage and may be used to successfully manage deeper partial-thickness burns, donor sites or burns in areas of contour, where many other dressings might not be considered or be appropriate.
Declaration Of Interest:
None declared.
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