Related Experiment Video
Updated: Apr 6, 2026

In Vitro ELISA Test to Evaluate Rabies Vaccine Potency
Published on: May 11, 2020
Crimean-Congo Hemorrhagic Fever
Sara Shayan1, Mohammad Bokaean2, Mona Ranjvar Shahrivar3
1Department of Microbiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran sarashayaan@gmail.com.
Abstract:
Crimean-Congo hemorrhagic fever virus (CCHFV) is a member of the Bunyaviridae family and Nairovirus genus. The viral genome consists of 3 RNA segments of 12 kb (L), 6.8 kb (M), and 3 kb (S). Crimean-Congo hemorrhagic fever (CCHF) is the most widespread tickborne viral infection worldwide: it has been reported in many regions of Africa, the Middle East, and Asia. The geographical distribution of CCHFV corresponds most closely with the distribution of members of the tick genera, and Hyalomma ticks are the principal source of human infection. In contrast to human infection, CCHFV infection is asymptomatic in all species. Treatment options for CCHF are limited; immunotherapy and ribavirin are effective in the treatment of CCHF; the efficacy of ribavirin in the treatment of CCHF has not yet been proven. This article reviews the history, epidemiology, clinical symptoms, pathogenesis, diagnosis, and treatment of CCHFV, as well as the development of a vaccine against it.
Related Concept Videos
Cytomegalovirus Disease
Arboviral Encephalitis
Cholera
Viral Meningitis
Hepatitis
Infectious Diseases and Their Occurrence

