Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Micturition Reflex01:26

The Micturition Reflex

3.7K
Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
3.7K
Urinary Bladder01:23

Urinary Bladder

4.4K
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
4.4K
Anatomy of the Genitourinary System II: Bladder and Urethra01:19

Anatomy of the Genitourinary System II: Bladder and Urethra

2.9K
The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
2.9K
Urethra01:16

Urethra

6.3K
The urethra is a hollowed tubular organ through which urine is expelled from the body. This structure extends from the bladder to the external opening, allowing urine to be released.
The anatomy of the urethra differs between males and females. In females, the urethra is short, measuring about 3–4 cm in length, and opens anterior to the vaginal opening. In males, the urethra is longer and passes through the penis, serving dual purposes: expelling urine and ejaculating semen. The male...
6.3K
Muscles of the Pelvic Floor and Perineum01:26

Muscles of the Pelvic Floor and Perineum

6.0K
The muscles of the pelvic floor and perineum are crucial for supporting the pelvic organs, controlling continence, and aiding in sexual function, childbirth, and core stability. They are typically divided into the superficial perineal layer and the deep pelvic floor layer.
Perineal Layer
The perineum is a diamond-shaped area below the pelvic diaphragm, divided into an anterior urogenital triangle that contains the external genitals and a posterior anal triangle housing the anus. The urogenital...
6.0K
Urodynamic Studies: Uroflowmetry01:19

Urodynamic Studies: Uroflowmetry

7.9K
Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...
7.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hereditary spastic paraplegias: When to expect bladder dysfunction a genetic and urodynamic study.

European journal of neurology·2024
Same author

Association between frailty and detrusor overactivity with detrusor underactivity in older women.

Neurourology and urodynamics·2024
Same author

Is the time right for a new initiative in mathematical modeling of the lower urinary tract? ICI-RS 2023.

Neurourology and urodynamics·2023
Same author

RE to Jaskowak D, Nunez R, Ramachandran R, Alhajjar E, Yin J, Guidoboni G, Danziger ZC Mathematical modeling of the lower urinary tract: A review. 2022; 41(6): 1305-1315. 10.1002/nau.24995.

Neurourology and urodynamics·2023
Same author

Long-term functional outcomes of artificial urinary sphincter (AMS 800™) implantation in women aged over 75 years and suffering from stress urinary incontinence caused by intrinsic sphincter deficiency.

World journal of urology·2021
Same author

Detrusor contractility in post-menopausal women: Impact of ageing, complaint and urodynamic diagnosis.

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie·2021

Related Experiment Video

Updated: Apr 6, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
03:26

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

2.4K

Detrusor after-contraction: a new insight.

Francoise A Valentini1,2, Brigitte G Marti3, Gilberte Robain1,2

  • 1ER6 - Université Pierre & Marie Curie (Paris 06), Paris, France.

International Braz J Urol : Official Journal of the Brazilian Society of Urology
|July 23, 2015
PubMed
Summary

Detrusor after-contractions (DAC) are uncommon in adults and not linked to bladder outlet obstruction. These events are more likely associated with detrusor overactivity (DO) and appear to have weak clinical significance.

More Related Videos

A Decentralized Ex Vivo Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling
06:36

A Decentralized Ex Vivo Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling

Published on: November 28, 2019

7.8K
Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology
10:26

Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology

Published on: August 18, 2014

27.0K

Related Experiment Videos

Last Updated: Apr 6, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
03:26

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

2.4K
A Decentralized Ex Vivo Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling
06:36

A Decentralized Ex Vivo Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling

Published on: November 28, 2019

7.8K
Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology
10:26

Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology

Published on: August 18, 2014

27.0K

Area of Science:

  • Urology
  • Urodynamics

Background:

  • Detrusor after-contractions (DAC) lack a clear definition and their clinical significance, whether as an artifact or linked to detrusor overactivity (DO) or bladder outlet obstruction (BOO), is debated.
  • DAC are infrequent in adult urodynamic studies.

Purpose of the Study:

  • To analyze urodynamic parameters during voiding with DAC.
  • To simulate pathophysiological conditions using the VBN model to explain voiding and DAC.

Main Methods:

  • Analysis of a large urodynamic database identifying 60 patients (5.7%) with DAC.
  • DAC defined by post-void residual <30mL and detrusor pressure increase >10cmH2O.
  • VBN model used for pressure/flow curve analysis and simulations.

Main Results:

  • Onset of DAC (ODAC) occurred at Q=7.3±5.7mL/s and bladder volume=17.9±15.4mL.
  • Urgency-frequency syndrome and DO were frequent associations.
  • ODAC showed a detrusor pressure slope inversion without flow perturbation; no simulated condition fully explained the curves.

Conclusions:

  • No initial voiding urodynamic characteristic predicts DAC occurrence.
  • ODAC is linked to bladder collapse and likely associated with DO, not BOO.
  • DAC may result from local conditions in an emptying bladder and appears to have weak clinical significance.