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Blood pressure control and risk profile in poststroke survivors: a comparison with the general population
Renata Cífková1, Peter Wohlfahrt, Alena Krajčoviechová
1aCenter for Cardiovascular Prevention, First Medical School of Charles University in Prague and Thomayer Hospital, Prague bSecond Department of Internal Medicine, Charles University Medical Faculty and Teaching Hospital cBiomedical Center, Medical Faculty of Charles University, Pilsen dDepartment of Neurology, Thomayer Hospital, Prague eDepartment of Neurosurgery and Department of Neurology, University Hospital, Pilsen fMedical Statistics Unit, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Insights
Stroke survivors have high rates of uncontrolled hypertension and other cardiovascular risks. Poor management of these factors indicates gaps in secondary prevention strategies for stroke patients.
Area of Science:
- Cardiovascular Medicine
- Neurology
- Public Health
Background:
- Recurrent strokes lead to worse outcomes and higher costs than first-ever strokes.
- Secondary prevention through lifestyle changes and medication is crucial for stroke survivors.
- Understanding the prevalence of risk factors in stroke survivors is key for effective prevention.
Purpose of the Study:
- To determine the prevalence of hypertension and other cardiovascular risk factors in stroke survivors.
- To compare these risk factors between stroke survivors and a control population.
- To assess the control of these risk factors in post-stroke patients.
Main Methods:
- A study involving 424 post-stroke survivors examined 6-36 months after their first ischemic stroke.
- Comparison with age and geographically matched controls from the Czech MONICA study database.
- Assessment of hypertension, antihypertensive drug use, blood pressure control, statin use, cholesterol levels, smoking, obesity, and diabetes prevalence.
Main Results:
- Hypertension was highly prevalent (91.5% in survivors vs. 71.8% in controls).
- Blood pressure control was suboptimal, with only 49.5% of hypertensive survivors reaching target <140/90 mmHg.
- Significant rates of smoking, obesity (especially in women), and diabetes were observed, with poor low-density lipoprotein-cholesterol control.
Conclusions:
- There is a high prevalence and poor control of major cardiovascular risk factors in patients after their first ischemic stroke.
- These findings suggest inadequate implementation of secondary prevention guidelines in clinical practice.
- Improved management of hypertension and other risk factors is essential for reducing stroke recurrence.
Objective:
Recurrent strokes are associated with higher mortality, greater disability, and increased healthcare costs compared with first-ever stroke. Lifestyle measures and drug treatment in secondary prevention decrease the risk of recurrence while improving the quality of life of patients. The objective of this study was to determine the prevalence of hypertension and other cardiovascular risk factors in stroke survivors and population controls.
Methods And Results:
A total of 424 poststroke survivors (aged 66.0 ± 10.4 years) were examined 6-36 months after their first ischemic stroke. Controls of similar age and from the same geographic region were selected from the database of the Czech post-Multinational MONItoring of trends and determinants in CArdiovascular disease Study. Hypertension was found to be the most prevalent risk factor affecting 91.5% of stroke survivors and 71.8% of controls. Use of antihypertensive drugs was reported in 79.5% of stroke survivors and 56.7% of controls. However, blood pressure lower than 140/90 mmHg was achieved in only 49.5% of hypertensive stroke survivors. More than 60% of stroke survivors used statins but low-density lipoprotein-cholesterol lower than 2.5 mmol/l was achieved in only 47.4 and 37% of male and female poststroke survivors, respectively. About a third of poststroke patients continue to smoke, and obesity is a major problem, particularly in women (prevalence 47%), who also have a high prevalence of diabetes.
Conclusion:
We found a high prevalence and poor control of major cardiovascular risk factors in patients surviving their first-ever ischemic stroke, thus showing poor implementation of guidelines for secondary prevention in clinical practice.
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