Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Biofilms

Biofilms

Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cellular Crosstalk Within Magnetically Functionalised Hydrogel-Composite Scaffolds for Enhanced Vascularisation and Bone Repair.

Gels (Basel, Switzerland)·2026

Same author

An in vitro study on the antimicrobial efficacy of a calcium hydroxide versus a calcium silicate-based endodontic medicament.

Clinical oral investigations·2025

Same author

Multi-doped glasses with Mg<sup>2+</sup> and Zn<sup>2+</sup> ions in glass-ionomer cements.

Dental materials : official publication of the Academy of Dental Materials·2025

Same author

Hydrogel Composite Magnetic Scaffolds: Toward Cell-Free In Situ Bone Tissue Engineering.

ACS applied bio materials·2023

Same author

A self-etch bonding system with potential to eliminate selective etching and resist proteolytic degradation.

Journal of dentistry·2023

Same author

Performance of novel enamel-conditioning calcium-phosphate pastes for orthodontic bonding: An <i>in vitro</i> study.

Journal of clinical and experimental dentistry·2023

Same journal

Preface.

Frontiers of oral biology·2016

Same journal

Conclusion and Future Directions.

Frontiers of oral biology·2015

Same journal

A Comparison between Osteotomy and Corticotomy-Assisted Tooth Movement.

Frontiers of oral biology·2015

Same journal

Photobiomodulation and Lasers.

Frontiers of oral biology·2015

Same journal

Corticision: A Flapless Procedure to Accelerate Tooth Movement.

Frontiers of oral biology·2015

Same journal

Piezocision™: Accelerating Orthodontic Tooth Movement While Correcting Hard and Soft Tissue Deficiencies.

Frontiers of oral biology·2015

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 6, 2026

Oral Biofilm Formation on Different Materials for Dental Implants

Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

Biomaterials in Relation to Dentistry.

Sanjukta Deb¹, Simran Chana

¹Division of Tissue Engineering and Biophotonics, King's College London Dental Institute, Guy's Hospital, London, UK.

Frontiers of Oral Biology

|July 24, 2015

Summary

This summary is machine-generated.

Dental caries is a major oral health challenge. This chapter reviews current direct restorative biomaterials, emphasizing the need for advanced, minimally invasive options due to amalgam phase-out and tissue regeneration limitations.

More Related Videos

Accessing the Cytotoxicity and Cell Response to Biomaterials

Accessing the Cytotoxicity and Cell Response to Biomaterials

Published on: July 8, 2021

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Related Experiment Videos

Last Updated: Apr 6, 2026

Oral Biofilm Formation on Different Materials for Dental Implants

Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

Accessing the Cytotoxicity and Cell Response to Biomaterials

Accessing the Cytotoxicity and Cell Response to Biomaterials

Published on: July 8, 2021

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Area of Science:

Dental Biomaterials Science
Restorative Dentistry
Oral Health Research

Background:

Dental caries is a prevalent biofilm-dependent disease causing tooth structure destruction.
Current restorative materials like amalgam face phase-out due to environmental concerns (Minamata Convention).
Significant healthcare burden exists despite advances in caries prevention and restoration.

Purpose of the Study:

To present the current state of direct restorative biomaterials in dentistry.
To discuss the role and future of these materials in modern dental practice.
To highlight the importance of developing advanced biomaterials for minimally invasive dentistry.

Main Methods:

Review of current literature on direct restorative biomaterials.
Analysis of the properties and clinical performance of existing dental materials.
Exploration of emerging trends, including tissue engineering and biomimetic approaches.

Main Results:

Dental biomaterials are crucial for restoring tooth structure, but clinical performance concerns exist.
Amalgam use is declining due to mercury regulations, necessitating alternative materials.
Development of inexpensive, stable, and easy-to-handle restorative materials is essential.
Regenerative treatments show promise but have limited application for enamel and dentine remineralization.

Conclusions:

The development of smart biomaterials is critical for minimally invasive dentistry.
Preservation of natural tooth tissue is a key principle of modern restorative approaches.
Future dental materials must balance aesthetics, function, and environmental considerations.