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Updated: Apr 6, 2026

The Influence of Liver Resection on Intrahepatic Tumor Growth
Published on: April 9, 2016
Growth factors enhance liver regeneration in acute-on-chronic liver failure
Chandan Kumar Kedarisetty1, Lovkesh Anand1, Arshi Khanam2
1Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.
Abstract:
Acute-on-chronic liver failure is a distinct syndrome characterized by a rapid progression of liver disease culminating in organ failure and death. The only definitive treatment is liver transplantation. However, there is a possible element of reversibility and hepatic regeneration if the acute insult can be tided over. Exogenously administered growth factors may stimulate hepatocytes, hepatic progenitor cells and bone marrow-derived cells to supplement hepatic regeneration. The proposed review is intended to provide an in-depth analysis of the individual components of hepatic and bone marrow niches and highlight the growing role of various growth factors in liver regeneration in health and in liver failure.
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