Mid-Term Outcomes of Endovascular Treatment for TASC-II D Femoropopliteal Occlusive Disease with Critical Limb
Álvaro Torres-Blanco1, Gemma Edo-Fleta2, Francisco Gómez-Palonés2
1Department of Angiology, Endovascular and Vascular Surgery, Hospital Universitario Dr. Peset, Av/Gaspar Aguilar 90, 46017, Valencia, Spain. atorres658@yahoo.es.
Insights
Endovascular treatment for Trans-Atlantic Inter-Society Consensus II (TASC-II) D femoropopliteal occlusions in critical limb ischemia (CLI) patients is safe and effective. While restenosis necessitates follow-up, this minimally invasive approach offers good outcomes.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Endovascular Interventions
Background:
- Critical limb ischemia (CLI) poses significant challenges, often linked to complex femoropopliteal occlusions.
- Trans-Atlantic Inter-Society Consensus II (TASC-II) D lesions represent the most challenging category of femoropopliteal disease.
Purpose of the Study:
- To evaluate the safety and midterm effectiveness of endovascular treatment for TASC-II D femoropopliteal occlusions in patients with CLI.
- To assess outcomes including limb salvage, revascularization rates, and patency.
Main Methods:
- Retrospective analysis of 32 CLI patients with TASC-II D femoropopliteal occlusions treated between 2008-2013.
- Data included lesion characteristics, interventions (stent, stent-graft, angioplasty), and clinical outcomes.
- Kaplan-Meier and Cox analyses assessed limb salvage, freedom from target lesion revascularization (TLR), and freedom from target extremity revascularization (TER).
Main Results:
- 35 TASC-II D occlusions were treated in 32 patients (mean age 76, 80% with tissue loss).
- 2-year freedom from TLR and TER rates were 41% and 76%, respectively.
- Primary and secondary patency rates at 2 years were 41% and 79%, with 7 major amputations and 6 deaths during follow-up.
Conclusions:
- Endovascular treatment for TASC-II D lesions in CLI patients is safe and yields satisfactory midterm results.
- A minimally invasive approach is beneficial for this patient group.
- Regular follow-up is crucial due to a high rate of restenosis, necessitating further long-term efficacy studies.
Purpose:
The purpose of the study was to assess the safety and midterm effectiveness of endovascular treatment in Trans-Atlantic Inter-Society Consensus II (TASC-II) D femoropopliteal occlusions in patients with critical limb ischemia (CLI).
Methods:
Patients with CLI who underwent endovascular treatment for TASC-D de novo femoropopliteal occlusive disease between September 2008 and December 2013 were selected. Data included anatomic features, pre- and postprocedure ankle-brachial index, duplex ultrasound, and periprocedural complications. Sustained clinical improvement, limb salvage rate, freedom from target lesion revascularization (TLR), and freedom from target extremity revascularization (TER) were assessed by Kaplan-Meier estimation and predictors of restenosis/occlusion with Cox analysis.
Results:
Thirty-two patients underwent treatment of 35 TASC-D occlusions. Mean age was 76 ± 9. Mean lesion length was 23 ± 5 cm. Twenty-eight limbs (80 %) presented tissue loss. Seventeen limbs underwent treatment by stent, 13 by stent-graft, and 5 by angioplasty. Mean follow-up was 29 ± 20 months. Seven patients required major amputation and six patients died during follow-up. Eighteen endovascular and three surgical TLR procedures were performed due to restenosis or occlusion. Estimated freedom from TLR and TER rates at 2 years were 41 and 76%, whereas estimated primary and secondary patency rates were 41 and 79%, respectively.
Conclusions:
Endovascular treatment for TASC II D lesions is safe and offers satisfying outcomes. This patient subset would benefit from a minimally invasive approach. Follow-up is advisable due to a high rate of restenosis. Further follow-up is necessary to know the long-term efficacy of these procedures.
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