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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Acne Infection01:27

Acne Infection

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Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
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Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

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A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
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Papillary Dermis01:11

Papillary Dermis

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
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Accessory Structures of the Skin: Hair Growth and Types01:20

Accessory Structures of the Skin: Hair Growth and Types

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Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
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Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

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Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
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Related Experiment Video

Updated: Apr 6, 2026

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
03:22

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

Published on: January 27, 2018

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Psoriatic alopecia.

S M C George1, M R Taylor2, P B J Farrant3

  • 1Department of Dermatology, Eastbourne District General Hospital, Eastbourne, UK.

Clinical and Experimental Dermatology
|July 24, 2015
PubMed
Summary
This summary is machine-generated.

Psoriasis can cause various hair loss conditions, including psoriatic alopecia and increased risk of alopecia areata. Treatments for psoriasis may also contribute to hair abnormalities and hair loss.

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Last Updated: Apr 6, 2026

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Area of Science:

  • Dermatology
  • Trichology

Background:

  • Alopecia and hair abnormalities in psoriasis patients have been noted for over 40 years.
  • Psoriatic alopecia remains underrecognized by clinicians.
  • Hair loss can be directly linked to psoriasis, affecting scalp and body hair.

Purpose of the Study:

  • To review the clinical and histological features of psoriatic alopecia.
  • To discuss the association between psoriasis and alopecia areata.
  • To examine the impact of psoriasis treatments on hair health.

Main Methods:

  • Review of existing literature on psoriasis and associated hair loss.
  • Analysis of histological findings in psoriatic alopecia.
  • Examination of epidemiological data on psoriasis and alopecia areata.

Main Results:

  • Psoriatic alopecia can manifest as scalp lesions or generalized telogen effluvium, with potential for scarring.
  • Histological features include interfollicular psoriasis, perifollicular inflammation, and sebaceous gland changes.
  • Psoriasis patients have an elevated risk for alopecia areata, and treatments can exacerbate hair loss.

Conclusions:

  • Psoriatic alopecia is a complex condition with diverse clinical presentations and histological findings.
  • The interplay between psoriasis, alopecia areata, and treatment side effects requires clinical attention.
  • Further research is needed to understand and manage hair loss in psoriasis patients.