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Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
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The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
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Acute Pancreatitis II: Clinical Manifestations and Management01:30

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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Acute Pancreatitis I: Introduction01:27

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Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
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Chronic Pancreatitis II: Collaborative Care01:29

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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
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The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
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Decrease in the Prevalence of Pancreatitis Associated with Primary Hyperparathyroidism: Experience at a Tertiary

Marcela Janka-Zires1, Jorge Hernández-Calleros2, Francisco Javier Gómez-Pérez1

  • 1Department of Endocrinology and Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, D.F., Mexico.

Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion
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The prevalence of pancreatitis linked to primary hyperparathyroidism decreased from 12.1% to 6.7% at a major Mexican medical center. This study tracked cases between 1987 and 2012, noting fewer associated risk factors like alcohol and gallstones.

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Area of Science:

  • Endocrinology
  • Gastroenterology
  • Epidemiology

Background:

  • Hypercalcemia is a recognized cause of acute and chronic pancreatitis, primarily linked to primary hyperparathyroidism.
  • The prevalence of pancreatitis in primary hyperparathyroidism patients varies globally, influenced by additional disease factors.
  • A 1988 study at INCMNSZ reported a 12.1% prevalence of pancreatitis secondary to primary hyperparathyroidism.

Purpose of the Study:

  • To determine the current prevalence of pancreatitis associated with primary hyperparathyroidism at the Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ).

Main Methods:

  • A retrospective review of 385 primary hyperparathyroidism cases was conducted.
  • The study period spanned from 1987 to 2012.
  • Cases with documented acute or chronic pancreatitis were identified and analyzed.

Main Results:

  • A prevalence of 6.7% for pancreatitis associated with primary hyperparathyroidism was found, a decrease from the previously reported 12.1%.
  • Associated risk factors showed a decline: alcohol consumption (20% vs. 32.0%), gallstones (10% vs. 34.6%), and ureteral calculi (20% vs. 40.0%).
  • Average calcium levels were comparable between the two study periods (13.1 mg/dl vs. 13.8 mg/dl).

Conclusions:

  • The prevalence of pancreatitis secondary to primary hyperparathyroidism has decreased at INCMNSZ.
  • This decline suggests potential changes in disease management or patient population over time.