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Related Concept Videos

Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

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Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
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Autoimmune Disorders01:29

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Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
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Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
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Viral Meningitis01:18

Viral Meningitis

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Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
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Arboviral Encephalitis01:25

Arboviral Encephalitis

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Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
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Myasthenia Gravis: Overview and Treatment01:20

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Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
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Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
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Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

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Immune-Mediated Neurological Disorders.

Teerin Liewluck1, Augusto Miravalle

  • 1University of Colorado Anschutz Medical Campus, 12631 E. 17th Avenue, Mail Stop B185, Aurora, CO, 80045, USA, Teerin.lieluck@ucdenver.edu.

Current Neurology and Neuroscience Reports
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PubMed
Summary
This summary is machine-generated.

Autoimmune disorders are a growing cause of neurological conditions. This review covers new insights into the causes, symptoms, and diagnosis of these immune-mediated neurological disorders.

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Area of Science:

  • Neurology
  • Immunology

Background:

  • Autoimmune disorders are increasingly implicated in neurological conditions.
  • These disorders lead to significant clinical disability.

Purpose of the Study:

  • Review recent advancements in understanding immune-mediated neurological disorders.
  • Discuss pathophysiology, clinical presentations, and diagnostic approaches.

Main Methods:

  • Literature review of recent developments.
  • Synthesis of current theories on autoimmunity and environmental factors.

Main Results:

  • Exploration of pathophysiology and clinical features.
  • Identification of diagnostic tools and potential biomarkers.

Conclusions:

  • Autoimmune disorders represent a significant challenge in neurology.
  • Biomarkers may offer diagnostic and pathogenetic insights.