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Uveitis attack and drug reaction due to cefuroxime axetil

Canan Akman1, Arif Duran2, Utku Murat Kalafat1

  • 1a Department of Emergency Medicine , Kanuni Training and Research Hospital , Istanbul , Turkey and.

Cutaneous and Ocular Toxicology
|July 24, 2015
PubMed

Insights

This case study discusses a rare adverse drug reaction in a patient who developed uveitis and skin lesions after taking cefuroxime axetil for tonsillitis. It highlights potential antibiotic side effects beyond bacterial infections.

Area of Science:

  • Ophthalmology
  • Dermatology
  • Pharmacology

Background:

  • Antibiotics are crucial for bacterial infections but can cause adverse reactions.
  • Cefuroxime axetil is a common antibiotic used for acute tonsillitis.

Observation:

  • A 30-year-old female presented with bilateral eye redness, photophobia, ear swelling/pain, and lip eruptions.
  • Symptoms appeared after a course of cefuroxime axetil for acute tonsillitis.

Findings:

  • The patient developed uveitis and mucocutaneous lesions, suggesting a severe drug reaction.
  • The timing of symptoms points to cefuroxime axetil as the likely causative agent.

Implications:

  • This case underscores the importance of monitoring for non-bacterial side effects of antibiotics.
  • Clinicians should consider drug-induced uveitis and dermatological reactions in patients with relevant symptoms.
  • Further research into antibiotic-specific adverse reactions is warranted.
Keywords:
Cefuroxime axetildrug reactionuveitis

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