Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mitogens and the Cell Cycle02:38

Mitogens and the Cell Cycle

8.4K
Mitogens and their receptors play a crucial role in controlling the progression of the cell cycle. However, the loss of mitogenic control over cell division leads to tumor formation. Therefore, mitogens and mitogen receptors play an important role in cancer research. For instance, the epidermal growth factor (EGF) - a type of mitogen and its transmembrane receptor (EGFR), decides the fate of the cell's proliferation. When EGF binds to EGFR, a member of the ErbB family of tyrosine kinase...
8.4K
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

5.1K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
5.1K
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

1.7K
1.7K
Regulation of Food Intake01:30

Regulation of Food Intake

3.2K
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
3.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SGLT2 Inhibitors Between Benefits and Euglycemic Ketoacidosis: A Concise Review.

International journal of molecular sciences·2026
Same author

Correction: Pînzariu et al. Gut Microbiota and Short-Chain Fatty Acids: Key Factors in Pediatric Obesity and Therapeutic Targets. <i>Int. J. Mol. Sci.</i> 2025, <i>26</i>, 11503.

International journal of molecular sciences·2026
Same author

Gut Microbiome Responses to Nutritional and Lifestyle Interventions in Pediatric Obesity: A Systematic Review Toward Precision Nutrition.

Children (Basel, Switzerland)·2026
Same author

Thyroid Autoimmunity in Polycystic Ovary Syndrome: Phenotype Distribution, HDL-Cholesterol, and Data-Driven Clusters in a Retrospective Cohort Study.

Medicina (Kaunas, Lithuania)·2026
Same author

Exploratory Real-World Observations on Pulmonary Function Evolution, HRCT Patterns, and Antifibrotic Escalation in Systemic Sclerosis-Associated Interstitial Lung Disease Treated with Mycophenolate Mofetil.

Journal of clinical medicine·2026
Same author

Tear biomarker changes and ocular surface recovery with low-level light therapy after cataract surgery: a double-masked randomized controlled clinical trial.

Scientific reports·2026

Related Experiment Video

Updated: Apr 6, 2026

Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment
11:13

Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment

Published on: June 9, 2023

2.5K

IMPLICATIONS OF GHRELIN AXIS IN BREAST CANCER--REVIEW.

Ioana Armasu, C Volovăt, V L Drug

    Revista Medico-Chirurgicala a Societatii De Medici Si Naturalisti Din Iasi
    |July 25, 2015
    PubMed
    Summary

    Ghrelin hormone may influence breast cancer development and could be a diagnostic marker or therapeutic target. Further research is needed to confirm its precise role in breast cancer pathogenesis.

    More Related Videos

    A Modified In vitro Invasion Assay to Determine the Potential Role of Hormones, Cytokines and/or Growth Factors in Mediating Cancer Cell Invasion
    06:36

    A Modified In vitro Invasion Assay to Determine the Potential Role of Hormones, Cytokines and/or Growth Factors in Mediating Cancer Cell Invasion

    Published on: April 24, 2015

    11.5K
    Studying TGF-&#946; Signaling and TGF-&#946;-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
    06:54

    Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

    Published on: October 27, 2020

    14.8K

    Related Experiment Videos

    Last Updated: Apr 6, 2026

    Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment
    11:13

    Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment

    Published on: June 9, 2023

    2.5K
    A Modified In vitro Invasion Assay to Determine the Potential Role of Hormones, Cytokines and/or Growth Factors in Mediating Cancer Cell Invasion
    06:36

    A Modified In vitro Invasion Assay to Determine the Potential Role of Hormones, Cytokines and/or Growth Factors in Mediating Cancer Cell Invasion

    Published on: April 24, 2015

    11.5K
    Studying TGF-&#946; Signaling and TGF-&#946;-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
    06:54

    Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

    Published on: October 27, 2020

    14.8K

    Area of Science:

    • Endocrinology
    • Oncology
    • Molecular Biology

    Background:

    • Breast cancer is the most common cancer in women.
    • Emerging evidence suggests the hormone ghrelin plays a role in breast cancer.
    • Ghrelin is known for regulating growth hormone release and appetite.

    Purpose of the Study:

    • To systematically review the literature on the role of the ghrelin axis in breast cancer pathogenesis.
    • To evaluate ghrelin as a potential diagnostic marker and therapeutic target for breast cancer.

    Main Methods:

    • A systematic review of studies was conducted using the PubMed Database.
    • Ten relevant papers were included in the analysis.

    Main Results:

    • The ghrelin axis appears to be involved in breast cancer pathogenesis.
    • The exact role of the ghrelin axis in breast cancer requires further elucidation.

    Conclusions:

    • The ghrelin axis is implicated in breast cancer development.
    • Larger studies analyzing metabolic, genetic, and environmental factors are necessary to confirm the precise role of ghrelin in breast cancer.