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Bilateral hypoplastic internal carotid arteries with multiple cerebral aneurysms
K Kawai1, H Takahashi, F Ikuta
1Department of Pathology, Niigata University, Japan.
Clinical Neuropathology
|November 1, 1989
Summary
A rare case of subarachnoid hemorrhage is presented. Diminutive internal carotid arteries and cerebral aneurysms were found, linked to fibrous tissue occlusion.
Area of Science:
- Neurology
- Pathology
- Vascular Biology
Background:
- Subarachnoid hemorrhage (SAH) is a critical neurovascular event.
- Cerebral aneurysms are a common cause of SAH.
- Internal carotid artery (ICA) occlusion can lead to severe neurological deficits.
Observation:
- A 60-year-old male presented with massive SAH.
- Radiological imaging revealed bilateral ICA occlusion and multiple saccular cerebral aneurysms.
- Postmortem examination confirmed markedly diminutive ICAs occluded by mesenchymal fibrous tissue.
Findings:
- The primary finding was the association of diminutive ICAs, occluded by fibrous tissue, with cerebral aneurysms and SAH.
- Histopathological analysis identified mesenchymal fibrous tissue as the cause of ICA occlusion.
- The specific pathogenesis linking ICA stenosis/occlusion to aneurysm formation in this case was discussed.
Implications:
- This case highlights an unusual etiology for SAH, involving congenital or acquired ICA hypoplasia and subsequent fibrous occlusion.
- Understanding this rare pathogenesis may offer insights into aneurysm formation mechanisms.
- Further research into the relationship between carotid artery anomalies and cerebral aneurysms is warranted.