Related Experiment Video
Updated: Apr 6, 2026
11:20
Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
4.5K
23-gauge transconjunctival vitrectomy in eyes with pre-existing functioning filtering blebs
Seong Taeck Kim1, Gwang Rae Shin2, Ji Man Park3
1Department of Ophthalmology, Chosun University School of Medicine, 365# Philmun-daero street, Dong-gu, Gwangju District, 501-717, Republic of Korea. s20age@hanmail.net.
BMC Ophthalmology
|July 25, 2015
Summary
Transconjunctival pars plana vitrectomy (23G PPV) improved visual acuity in patients with prior trabeculectomy. This vitreoretinal surgery did not negatively impact the function of existing filtering blebs.
Area of Science:
- Ophthalmology
- Surgical Innovation
Background:
- Investigating the safety and efficacy of 23-gauge transconjunctival pars plana vitrectomy (23G PPV) in patients with pre-existing trabeculectomy.
- Assessing the impact of PPV on the function of filtering blebs in glaucoma patients.
Purpose of the Study:
- To evaluate the visual acuity, intraocular pressure (IOP), and bleb morphology after 23G PPV in patients with prior trabeculectomy.
- To determine if 23G PPV adversely affects the function of filtering blebs.
Main Methods:
- Retrospective review of 11 eyes undergoing 23G PPV with functioning filtering blebs post-trabeculectomy.
- Measurement of visual acuity, IOP, and subconjunctival fluid height via anterior segment OCT before and after surgery.
Main Results:
- Significant improvement in visual acuity was observed post-23G PPV (P = 0.003).
- No statistically significant changes in intraocular pressure (P = 0.758) or subconjunctival fluid height (P = 0.172) were noted.
- 23G PPV maintained IOP and bleb morphology.
Conclusions:
- 23-gauge transconjunctival pars plana vitrectomy is a safe procedure for patients with prior trabeculectomy.
- The surgical technique does not compromise the function of established filtering blebs.
Related Concept Videos
01:28Angle Closure Glaucoma: Treatment
1.7K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.7K
01:25Glaucoma: Overview
1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
01:27Open Angle Glaucoma: Treatment
1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K