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Fluorescence-Activated Cell Sorting for the Isolation of Scleractinian Cell Populations
Published on: May 31, 2020
Bioactive cembranoids from the South China Sea soft coral Sarcophyton elegans
Xin Liu1, Junsheng Zhang2, Qiao Liu3
1School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. liux66@mail2.sysu.edu.cn.
Abstract:
Four new cembranoids, sarcophelegans A-D (1-4) and six known analogues (5-10) were isolated from the South China Sea soft coral Sarcophyton elegans. Their structures were elucidated through detailed spectroscopic analysis, and the absolute configuration of 1 was confirmed by single-crystal X-ray diffraction. The antimigratory potential of compounds 1-10 were evaluated and compounds 2 and 6 were found to inhibit human breast tumor MDA-MB-231 cell migration at 10 μM.
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