[Cytosol estrogen, progestin receptors and secretory endometrium in infertile women]

The serum levels of estradiol (E2), progesterone (P), FSH, PRL and cytosol estrogen and progestin receptors (EcR, PcR) contents in the endometrial tissues were analyzed in patients with inadequate secretory endometrium. The result shows that EcR and PcR are significantly lower (EcR: P less than 0.01; PcR: P less than 0.05) in these patients than those of control group. The inadequate secretory changes of endometrium correlated with insufficient EcR and PcR contents rather than with decreased levels of serum E2, P, FSH and PRL. The authors suggest that during treatment of such patients both the hormonal levels in the peripheral blood and the EcR, PcR contents in the tissue should be considered at the same time.