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Updated: Apr 6, 2026

Extraction of Venom and Venom Gland Microdissections from Spiders for Proteomic and Transcriptomic Analyses
Published on: November 3, 2014
Troponin elevation after black widow spider envenomation
1*Department of Emergency Medicine,Brody School of Medicine,East Carolina University,Greenville,NC.
Black widow spider bites can cause rare cardiac complications. This case highlights an elderly man with elevated cardiac biomarkers and rhabdomyolysis after a western black widow spider bite.
Area of Science:
- Toxicology
- Cardiology
- Emergency Medicine
Background:
- Black widow spider envenomation typically causes localized pain, manageable with standard emergency department treatments.
- Severe complications, though uncommon, may necessitate admission or antivenom therapy.
Observation:
- An 84-year-old male presented with chest pain and dyspnea following a western black widow spider bite.
- Initial cardiac troponin I levels were elevated, peaking at 0.17 ng/ml, indicating potential myocardial injury.
- The patient also developed rhabdomyolysis, an unusual complication of black widow envenomation.
Findings:
- Elevated cardiac biomarkers, such as troponin I, are rarely reported in black widow spider envenomation.
- This case demonstrates a rare presentation of western black widow spider bite with cardiac involvement and rhabdomyolysis.
- The study discusses potential causes for elevated cardiac biomarkers in this context.
Implications:
- Clinicians should consider rare cardiac complications in patients presenting with symptoms after black widow spider bites.
- Prompt recognition and management of severe envenomation symptoms, including cardiac biomarkers and rhabdomyolysis, are crucial.
- Further research into the cardiovascular effects of black widow spider venom is warranted.
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