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Two new lignans from twigs of Aglaia odorata
Lei Peng1,2, Wu-Xiang Fu3, Chun-Xia Zeng3
1a College of Horticulture and Landscape, Yunnan Agriculture University , Kunming 650201 , China.
Journal of Asian Natural Products Research
|July 25, 2015
Abstract:
HPLC-guided separation of twigs of Aglaia odorata led to the isolation of eight lignans, including two new ones, 3'-methoxy-N-demethylrocaglamide (1) and 4'-O-demethyl-deacetylaglaxiflorin A (2). Compound 1 showed excellent cytotoxicity against three human cancer cell lines, HeLa, SGC-7901 gastric cancer, and A-549 lung cancer with the values of 0.32, 0.12, and 0.25 μM, respectively.
