An unusual cause of ventriculoperitoneal shunt infection

Majid Esmaeilzadeh1, Ariyan Pirayesh Islamian, Josef M Lang

  • 1At the Hannover Medical School in Hannover, Germany, Majid Esmaeilzadeh and Ariyan Pirayesh Islamian are residents in the Department of Neurosurgery; Josef M. Lang is head of the neurosurgical ICU in the neurosurgery clinic; Mathias Hornef is a professor at the Institute for Medical Microbiology and Hospital Epidemiology; Sebastian Suerbaum is a professor and chair at the Institute for Medical Microbiology and Hospital Epidemiology; and Joachim K. Krauss is a professor and department chair of the Department of Neurosurgery. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Insights

Ventriculoperitoneal shunt infections caused by Serratia marcescens are challenging. This study details successful treatment of two patients with S. marcescens shunt infection, notably without underlying abdominal disease.

Area of Science:

  • Neurosurgery
  • Infectious Diseases
  • Microbiology

Background:

  • Ventriculoperitoneal (VP) shunts are crucial for managing hydrocephalus.
  • Infections associated with VP shunt implantation pose significant clinical challenges.
  • Serratia marcescens, a gram-negative anaerobic rod, is an uncommon cause of VP shunt infections, often linked to abdominal pathology.

Observation:

  • This study presents two cases of VP shunt infection.
  • The causative agent identified in both cases was Serratia marcescens.
  • Neither patient had any identifiable underlying abdominal disease, a deviation from typical presentations.

Findings:

  • Successful treatment of VP shunt infection caused by Serratia marcescens was achieved in both patients.
  • The treatment approach effectively managed the infection despite the absence of predisposing abdominal conditions.
  • This highlights the possibility of treating S. marcescens VP shunt infections even in atypical cases.

Implications:

  • The findings suggest that VP shunt infections with Serratia marcescens can occur and be successfully treated without underlying abdominal disease.
  • This expands the understanding of S. marcescens VP shunt infections and their management.
  • Clinicians should consider S. marcescens in the differential diagnosis of VP shunt infections, even in the absence of typical risk factors.

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