Related Experiment Video
Updated: Apr 6, 2026

07:49
Stepwise Cell Seeding on Tessellated Scaffolds to Study Sprouting Blood Vessels
Published on: January 14, 2021
4.1K
Unstructured hexahedral mesh generation of complex vascular trees using a multi-block grid-based approach
Joris Bols1,2, L Taelman2, G De Santis2
1a Department of Flow Heat and Combustion Mechanics , Ghent University , Sint-Pietersnieuwstraat 41, Gent 9000 , Belgium.
Summary
This study introduces a novel hexahedral meshing approach for patient-specific vascular models. This method reduces computational time and operator effort for complex geometries, improving simulation accuracy.
Area of Science:
- Computational fluid dynamics
- Medical imaging and simulation
- Biomedical engineering
Background:
- Realistic numerical models of patient-specific vascular structures require significant computational resources.
- Traditional hexahedral grids reduce computation time but increase operator time and decrease cell quality for complex geometries.
- Existing hexahedral meshing methods often lack local refinement capabilities.
Purpose of the Study:
- To present a novel hexahedral meshing approach combining automated multi-block structures and a grid-based method.
- To overcome limitations of existing meshing techniques for complex vascular geometries.
- To assess the robustness and performance of the proposed hexahedral meshing method.
Main Methods:
- Development of an automated multi-block hexahedral meshing technique.
- Application of the novel meshing approach to complex vascular geometries (aneurysms, stenoses, bifurcations).
- Performance evaluation through numerical simulations, including grid sensitivity analysis and fluid-structure interaction.
Main Results:
- The novel hexahedral meshing approach demonstrates robustness on complex vascular geometries.
- Grid sensitivity analysis shows comparable or improved performance against tetrahedral grids.
- Local grid refinement capability is successfully demonstrated in fluid-structure interaction simulations.
Conclusions:
- The proposed hexahedral meshing method effectively addresses limitations of traditional approaches for complex vascular modeling.
- This technique offers a balance between reduced computational cost and improved operator efficiency.
- The approach facilitates more accurate and efficient patient-specific vascular simulations.

