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Sweet's Syndrome: An Evidence-Based Report.

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Sweet's syndrome, a neutrophilic dermatosis, presents with painful skin lesions and systemic symptoms. Early diagnosis and treatment with corticosteroids or dapsone are crucial for managing this condition.

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Area of Science:

  • Dermatology
  • Internal Medicine
  • Pathology

Background:

  • Sweet's syndrome is a neutrophilic dermatosis.
  • It presents with acute onset of painful, erythematous skin lesions.
  • Histological findings include dense neutrophilic infiltrate.

Purpose of the Study:

  • To describe the clinical characteristics and management of Sweet's syndrome.
  • To analyze patient demographics and associated disorders.
  • To evaluate treatment outcomes for this rare condition.

Main Methods:

  • Retrospective case series of ten patients diagnosed within one year.
  • Clinical data collection including demographics, symptoms, and associated disorders.
  • Histopathological examination of skin biopsy specimens and treatment response assessment.

Main Results:

  • Seven females and three males, mean age 47.6 years, were diagnosed.
  • Associated disorders included diabetes, hypothyroidism, hypertension, and inflammatory bowel disease.
  • Lesions were primarily on the face, neck, and upper extremities; treated with corticosteroids or dapsone.

Conclusions:

  • Sweet's syndrome requires prompt diagnosis and management.
  • Neutrophilic infiltrate is a key diagnostic feature.
  • Corticosteroids and dapsone are effective treatment options.