Association of the Laennec staging system with degree of cirrhosis, clinical stage and liver function
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Updated: Apr 6, 2026
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Published on: January 19, 2024
Wei Wang1, Jiye Li2, Runhua Pan2
1Department of Hepatobiliary Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. w_w824@163.com.
Objectives:
The aim of this study was to investigate the association of the Laennec staging system with degree of cirrhosis, clinical stage and liver function.
Methods:
Liver biopsy was performed for 30 patients with hepatitis B cirrhosis to test the content of hydroxyproline in hepatic tissue, judge the degree of cirrhosis and determine the Laennec staging system. The association of the Laennec staging system with the degree of cirrhosis, clinical stage and liver function was compared.
Results:
The Laennec staging system had a close association with clinical stage, model for end-stage liver disease score and degree of cirrhosis (r = 0.58, p < 0.01; r = 0.60, p < 0.01; r = 0.53, p < 0.01).
Conclusions:
The Laennec histological grading system can to some extent reflect the degree of cirrhosis, clinical stage and liver function, and is expected to predict the incidence of patient complications in a useful way.
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