Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Corpus callosotomy in intractable epilepsy].

S Constantini, Z H Rappaport, P Lerman

    Harefuah
    |December 15, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Significant clinical and radiologic response to targeted therapy in pediatric cervicomedullary low-grade gliomas harboring the BRAFV600E mutation.

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2025
    Same author

    TROPHY registry - status report.

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2021
    Same author

    Multiple Brain Developmental Venous Anomalies as a Marker for Constitutional Mismatch Repair Deficiency Syndrome.

    AJNR. American journal of neuroradiology·2018
    Same author

    Spinal and Paraspinal Plexiform Neurofibromas in Patients with Neurofibromatosis Type 1: A Novel Scoring System for Radiological-Clinical Correlation.

    AJNR. American journal of neuroradiology·2017
    Same author

    Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis.

    Leukemia·2017
    Same author

    Cerebral Metabolism in Head Trauma1.

    Progress in neurological surgery·2016
    Same journal

    [Tennis Elbow Among Players].

    Harefuah·2026
    Same journal

    [Internal Medicine - My Mission].

    Harefuah·2026
    Same journal

    [Treatment of Morbid Obesity in Israel: GLP-1 Agonists Versus Bariatric Surgery - Clinical and Economic Aspects].

    Harefuah·2026
    Same journal

    [Baby steps: Post-operative Treatment Recommendations for Pediatric Tracheostomy in Israel].

    Harefuah·2026
    Same journal

    [Mastoiditis Caused by Fusobacterium Necrophorum: an Unusual Pathogen in a Well-Known Disease].

    Harefuah·2026
    Same journal

    [Cochlear Implantation in Single-Sided Deafness - Six Years of Follow-Up from Diagnosis and Consistent Use, Through Dedicated and Creative Auditory Learning, to the Development of Bilateral Central Processing Abilities].

    Harefuah·2026
    See all related articles

    Corpus callosotomy effectively treated medically intractable epilepsy in children and adolescents. Partial resection is sufficient, minimizing side effects and achieving significant seizure reduction.

    Area of Science:

    • Neurosurgery
    • Epileptology
    • Pediatric Neurology

    Context:

    • Medically intractable epilepsy often requires surgical intervention.
    • Corpus callosotomy is a surgical option for severe epilepsy.
    • Patient selection is crucial for successful surgical outcomes.

    Purpose:

    • To evaluate the efficacy and safety of corpus callosotomy in pediatric patients with intractable epilepsy.
    • To determine the optimal surgical approach (partial vs. complete) for corpus callosotomy.
    • To identify predictors of successful outcomes and long-term side effects.

    Summary:

    • Six males and three females, aged 2-17 years, underwent partial or complete corpus callosotomy for intractable epilepsy.
    • Patient selection was based on evidence of unilateral cerebral damage or nonlocalized seizure focus with contralateral spread.

    Related Experiment Videos

  • All patients demonstrated seizure reduction, with the best outcomes observed in those with atonic seizures.

    • Impact:

    • Partial corpus callosotomy can be as effective as complete resection, reducing the need for more extensive surgery.
    • Staged callosal resection minimizes long-term side effects.
    • Corpus callosotomy offers a viable treatment option for select pediatric epilepsy cases.