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Updated: Apr 6, 2026

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
Published on: August 2, 2021
Patients' subjective rating of mental health improvement in a randomised controlled trial
Karen P Hayhurst1, Richard J Drake1, Jennifer A Massie2
1Institute of Brain, Behaviour and Mental Health, The University of Manchester, Manchester, UK.
Abstract:
We used UK CUtLASS RCT data to establish that patients' rating of mental health improvement (baseline to week 12) correlated significantly with percentage symptom improvement (PANSS). In a regression analysis predictors of the patient's week 12 mental health rating were percentage change in positive symptoms (PANSS), DAI score and the patient's rating of side effects. Patients in an RCT were able to subjectively rate their mental health status, validated by objective improvement on the PANSS.
