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[The multitest in evaluating cellular immunity].

V Bettoli, M Selvi, A Ferlini

    Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Societa Italiana Di Dermatologia E Sifilografia
    |May 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

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    The skin plays a crucial role in immunity. Multitest, a reliable tool for screening cell-mediated immune deficiency, accurately assesses delayed cutaneous hypersensitivity in patients.

    Area of Science:

    • Immunology
    • Dermatology

    Context:

    • The skin's significant role in the immune system is increasingly recognized.
    • Evaluating cell-mediated immune responses is critical for diagnosing immunodeficiencies.
    • Delayed cutaneous hypersensitivity (DCH) is a key indicator of cellular immunity.

    Purpose:

    • To assess the utility and reliability of the Multitest system for screening cell-mediated immune deficiencies.
    • To compare Multitest results with clinical suspicion and other laboratory tests.

    Summary:

    • The Multitest system, containing seven antigens and a control, offers a reliable method for DCH evaluation.
    • A study of 138 patients with suspected immune deficiencies demonstrated the Multitest's effectiveness.
    • Results showed Multitest is a valuable and statistically significant tool for screening cellular immune deficiency.

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    Impact:

    • Provides a reliable and efficient method for diagnosing cell-mediated immune deficiencies.
    • Supports the integration of DCH testing into routine immunodeficiency screening protocols.
    • Highlights the importance of the skin's immune function and diagnostic capabilities.