Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cardiomyopathy IV: Restrictive Cardiomyopathy

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...

Asthma-II: Pathophysiology and Classification

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

Yield Criteria for Ductile Materials under Plane Stress

Yield Criteria for Ductile Materials under Plane Stress

In designing structural elements and machine parts using ductile materials, it is crucial to ensure that these components withstand applied stresses without yielding. Yielding is initially determined through a tensile test, which evaluates the material's response to uniaxial stress. However, tensile stress is insufficient when components face biaxial or plane stress conditions This condition requires advanced criteria to predict failure.
The Maximum Shearing Stress Criterion, also known as...

Assessment of the Cardiovascular System III: Palpation

Assessment of the Cardiovascular System III: Palpation

Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...

Chronic Bowel Disorders: Introduction

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

CDAI trajectories in patients with rheumatoid arthritis treated with abatacept in real-world.

Advances in rheumatology (London, England)·2026

Same author

Lessons from an early rheumatoid arthritis incident cohort.

Seminars in arthritis and rheumatism·2026

Same author

Evaluating machine learning tools to assist title and abstract screening in systematic literature reviews: a report based on the EULAR RA Management Recommendations Task Force.

Annals of the rheumatic diseases·2026

Same author

Racial minorities are under-represented in SLE clinical trials: A systematic review and meta-analysis.

Autoimmunity reviews·2026

Same author

Real-World Upadacitinib Persistence and Clinical Outcomes Among Canadian Patients with Inflammatory Arthritis from a Patient Support Program: The UPRAISE Study.

Rheumatology and therapy·2026

Same author

Efficacy of synthetic and biological DMARDs: a systematic literature review informing the 2025 update of the EULAR recommendations for the management of rheumatoid arthritis.

Annals of the rheumatic diseases·2026

Search research articles

Related Experiment Video

Updated: Apr 6, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

New Classification Criteria for Systemic Sclerosis (Scleroderma).

Janet E Pope¹, Sindhu R Johnson²

¹Department of Medicine, St. Joseph's Health Care, University of Western Ontario, 268 Grosvenor Street, London, Ontario N6A 4V2, Canada.

Rheumatic Diseases Clinics of North America

|July 27, 2015

Summary

This summary is machine-generated.

The new American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria enhance systemic sclerosis (SSc) identification for research. These criteria, including skin thickening and specific clinical features, offer improved sensitivity and specificity for SSc classification.

Keywords:

Classification criteria Diagnosis Performance Scleroderma Sensitivity Specificity Systemic sclerosis Validation

More Related Videos

Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research

Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research

Published on: October 13, 2023

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

Related Experiment Videos

Last Updated: Apr 6, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research

Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research

Published on: October 13, 2023

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

Area of Science:

Rheumatology
Immunology
Clinical Medicine

Background:

Systemic sclerosis (SSc) classification requires updated criteria for research accuracy.
Previous criteria had limitations in classifying SSc patients effectively for studies.

Observation:

The American College of Rheumatology (ACR) and European League Against Rheumatism (EULAR) developed new SSc classification criteria.
Key criteria include skin thickening proximal to metacarpophalangeal joints.
Seven additive items with numerical weights contribute to classification: skin thickening, fingertip lesions, telangiectasia, abnormal nail fold capillaries, lung involvement, Raynaud's phenomenon, and SSc-related autoantibodies.

Findings:

The revised ACR/EULAR criteria demonstrate good sensitivity and specificity for classifying SSc.
These criteria aim to improve patient classification for clinical studies.

Implications:

The new criteria enhance the ability to identify and study systemic sclerosis cohorts.
While valuable for classification, these criteria do not replace the need for diagnostic evaluation.