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Updated: Apr 6, 2026

Heterotypic Three-dimensional In Vitro Modeling of Stromal-Epithelial Interactions During Ovarian Cancer Initiation and Progression
Published on: August 28, 2012
Ovarian hilar proliferations resembling Sertoli cell tumours: microscopic neoplasms or non-neoplastic remnants?
Jennifer Taylor1, Blaise A Clarke2, Noori U Hasan3
1Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK.
Aims:
To describe four cases of incidentally detected microscopic ovarian hilar Sertoli cell proliferation, a phenomenon that, as far as we are aware, has not been previously reported, and to discuss the differential diagnosis of these lesions.
Methods And Results:
The proliferations occurred in women aged 35-62 years, and were composed of solid and hollow tubules that were morphologically and immunohistochemically in keeping with Sertoli cells. Two cases were bilateral.
Conclusions:
We feel that these uncommon proliferations are likely to represent non-neoplastic embryological remnants rather than hilar Sertoli cell tumours.
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