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Isolated ocular lichen planus in a child.
Estera Igras1, Susan Kennedy2, Emma Jane MacDermott3
1Department of Ophthalmology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland.
Summary
This case study details the first instance of isolated ocular lichen planus (LP) in a child, presenting as severe dry eye and conjunctival scarring. Treatment with immunosuppressants achieved disease remission.
Area of Science:
- Ophthalmology
- Dermatology
- Autoimmune Diseases
Background:
- Lichen planus (LP) is an autoimmune inflammatory condition affecting skin and mucous membranes.
- Ocular involvement in LP is rare and has not been previously documented in pediatric cases.
Observation:
- An 8-year-old girl presented with severe dry eye, conjunctival hyperemia, and bilateral symblepharon.
- Conjunctival biopsy revealed fibrinogen deposits, indicative of LP, without other immunoglobulin or complement deposition.
Findings:
- The diagnosis of isolated conjunctival lichen planus was made, as no skin or other mucosal lesions were present.
- The patient experienced sustained disease remission following treatment with oral and topical cyclosporine, methotrexate, and low-dose oral steroids.
Implications:
- This case establishes the first report of isolated ocular lichen planus in a pediatric patient.
- It highlights the importance of considering LP in children presenting with severe, unexplained ocular inflammatory conditions.
- The successful treatment regimen suggests potential therapeutic strategies for this rare condition in children.
