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The answer is not 42.

Chris R Triggle1

  • 1Departments of Medical Education and Pharmacology, Weill Cornell Medical College in Qatar, Qatar Foundation, Education City, P.O. Box 24144, Doha, Qatar.

Biochemical Pharmacology
|July 28, 2015
PubMed
Summary
This summary is machine-generated.

Pioneering research in receptor pharmacology and calcium channel antagonists by David Triggle has significantly advanced biomedical science over five decades. His work continues to influence cardiovascular disease treatment and scientific research methodologies.

Keywords:
Calcium channelsDavid TriggleImpact factorScientific achievementcitations

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Area of Science:

  • Biomedical Science
  • Pharmacology
  • Medicinal Chemistry

Background:

  • David Triggle's extensive 50-year career bridges chemistry and biology, focusing on receptor pharmacology.
  • Early work investigated adreno- and muscarinic receptors, progressing to cellular signaling and calcium homeostasis.

Discussion:

  • His research led to the identification and development of critical calcium channel antagonists.
  • These contributions have had a profound impact on treating cardiovascular diseases.

Key Insights:

  • Triggle's work exemplifies the successful integration of chemical principles with biological research.
  • The development of calcium channel antagonists represents a major therapeutic advancement.

Outlook:

  • Reflecting on Triggle's career highlights the evolution of scientific research, funding, and publication over 50 years.
  • Evaluating the long-term impact of scientific contributions in the context of technological change is crucial.