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Lymphocyte Subpopulations and Cytokine Levels in Experimental Hyperhomocysteinemia

E V Fefelova1, P P Tereshkov, A A Dutov

  • 1Chita State Medical Academy, Chita, Russia, fefelova.elena@mail.ru.

Bulletin of Experimental Biology and Medicine
|July 28, 2015
PubMed

Moderate exogenous hyperhomocysteinemia is associated with an increase in lymphocyte count (mainly at the expense of cytotoxic T cells), a 2-fold drop of the immunoregulatory index, and increase in TNF-α, IFN-γ, and IL-17α concentrations in the serum and in mononuclear cells. Homocysteine concentration in the mononuclears remains unchanged.

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