The influence of left ventricular geometry on left atrial phasic function in hypertensive patients

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Marijana Tadic1,2, Cesare Cuspidi3, Biljana Pencic1

  • 1a Cardiology Department, University Clinical Hospital Center "Dr. Dragisa Misovic - Dedinje" , Belgrade , Serbia.

Blood Pressure
|July 28, 2015
PubMed

Insights

Hypertension alters left atrial (LA) function, particularly in patients with left ventricular hypertrophy (LVH). Concentric and dilated LVH patterns negatively impact LA size and function, as shown by echocardiography.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Imaging

Background:

  • Hypertension is a major cardiovascular risk factor.
  • Left ventricular (LV) geometry changes in hypertension can affect left atrial (LA) function.
  • Understanding these effects is crucial for risk stratification.

Purpose of the Study:

  • To investigate left atrial (LA) phasic function in hypertensive patients.
  • To analyze LA function based on different left ventricular (LV) geometric patterns.
  • To compare two-dimensional (2DE) and three-dimensional (3DE) echocardiography findings.

Main Methods:

  • Cross-sectional study of 213 hypertensive subjects.
  • Utilized 2DE and 3DE echocardiography for complete cardiac assessment.
  • Classified LV geometry using updated criteria including LV mass index, LV end-diastolic diameter, and relative wall thickness.

Main Results:

  • LA volumes increased with progressive LVH (concentric and concentric-dilated).
  • LA reservoir and conduit functions were impaired in concentric and concentric-dilated LVH.
  • LA booster pump function increased in concentric, dilated, and concentric-dilated LVH.
  • 2DE strain analysis corroborated these findings.
  • LVH patterns were independently associated with LA enlargement.

Conclusions:

  • LV geometric patterns significantly impact LA phasic function.
  • Concentric and dilated LVH patterns exert the most detrimental effect on LA size and function.
  • 2DE and 3DE echocardiography are valuable tools for assessing these changes.
Abstract

Keywords:
Hypertensionleft atriumleft ventricular geometrythree-dimensional echocardiographytwo-dimensional speckle tracking

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