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Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
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Repeat Radiosurgery for Trigeminal Neuralgia.

Corbin A Helis1, John T Lucas, J Daniel Bourland

  • 1*Departments of Neurosurgery and ‡Radiation Oncology, Wake Forest Baptist Medical Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina.

Neurosurgery
|July 28, 2015
PubMed
Summary
This summary is machine-generated.

Repeat Gamma Knife radiosurgery (GKRS) effectively treats recurrent trigeminal neuralgia pain. Patients experiencing facial numbness and positive pain response after initial GKRS show better outcomes with repeat treatment.

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Area of Science:

  • Neurosurgery
  • Neurology
  • Radiation Oncology

Background:

  • Recurrent trigeminal neuralgia (TN) pain often necessitates repeat treatments.
  • Gamma Knife radiosurgery (GKRS) is an established option for recurrent TN, with reported success rates ranging from 68% to 95%.

Purpose of the Study:

  • To evaluate outcomes of repeat Gamma Knife radiosurgery (GKRS) for trigeminal neuralgia (TN).
  • To identify predictive factors for successful repeat GKRS in TN patients.

Main Methods:

  • Retrospective cohort study of 152 patients undergoing repeat GKRS for TN between 1999 and 2013.
  • Long-term follow-up data collected via chart review and telephone interviews.

Main Results:

  • 84% of patients achieved Barrow Neurological Institute (BNI) IIIb pain relief; 46% achieved BNI I.
  • 1-, 3-, and 5-year rates for BNI I pain relief were 63%, 50%, and 37%, respectively.
  • Facial numbness post-first GKRS and positive pain response to initial GKRS predicted better outcomes.

Conclusions:

  • Repeat Gamma Knife radiosurgery (GKRS) is effective for recurrent trigeminal neuralgia (TN).
  • Predictive factors for successful repeat GKRS include prior facial numbness and positive pain response to the first GKRS.