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Idiopathic extensive spontaneous venous thrombosis (a case report)
Journal of Postgraduate Medicine
|April 1, 1989
Summary
Two patients with spontaneous venous thrombosis and polyserositis experienced abnormal liver function tests despite normal coagulograms. One case resolved spontaneously, while the other required anticoagulant therapy.
Area of Science:
- Internal Medicine
- Hematology
- Gastroenterology
Background:
- Spontaneous venous thrombosis is a rare condition.
- Polyserositis, characterized by inflammation of serous membranes, can present with diverse symptoms.
- Liver function test abnormalities may indicate systemic involvement.
Observation:
- Two cases of extensive spontaneous venous thrombosis were observed.
- Both patients exhibited documented polyserositis.
- Transient liver function test abnormalities were noted in both patients.
Findings:
- Coagulograms were normal in both patients, ruling out common clotting disorders.
- One patient experienced a self-limiting illness.
- The second patient required anticoagulant treatment with coumarin derivatives.
Implications:
- This presentation suggests a potential link between polyserositis and spontaneous venous thrombosis.
- Further research is needed to elucidate the underlying mechanisms.
- Clinical vigilance for thrombotic events in polyserositis patients is warranted.