Transitional cell carcinoma arising in a tailgut cyst
Adnan A Sheikh1, Olorundi Rotimi1, Deepa Jacob1
1The John Goligher Colorectal Surgery Unit, St James University Hospital, Leeds LS9 7TF, UK.
Journal of Surgical Case Reports
|July 29, 2015
Summary
Malignant transformation in tailgut cysts (TGCs) is rare. This case report details a rare transitional cell carcinoma within a rectal-encapsulating TGC, discussing its pathology, diagnosis, and management.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Oncology
Background:
- Tailgut cysts (TGCs) are rare congenital remnants of the embryonic tailgut.
- Malignant transformation within TGCs is exceptionally uncommon.
- Transitional cell carcinoma (TCC) is a rare subtype of malignancy in TGCs.
Observation:
- A case of a patient presenting with a malignant TGC encasing the rectum.
- The tumor exhibited features of transitional cell carcinoma.
- Diagnostic imaging and pathological examination were crucial for identification.
Findings:
- This report documents the first case of transitional cell carcinoma arising in a tailgut cyst in the UK literature.
- The malignant TGC significantly impacted the rectal anatomy.
- Management involved surgical considerations for a locally advanced rectal tumor.
Implications:
- Highlights the importance of considering rare malignancies in TGCs.
- Emphasizes the need for thorough pathological evaluation of TGCs.
- Informs diagnostic and therapeutic strategies for similar rare rectal tumors.


