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Dose-response relationship between cigarette smoking and female sexual dysfunction.

Joohee Choi1, Dong Wook Shin2, Seungmee Lee1

  • 1Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.

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Current smoking is an independent risk factor for female sexual dysfunction (FSD) in premenopausal women. Higher cumulative smoking dose and nicotine dependency are associated with increased FSD risk.

Keywords:
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Area of Science:

  • Reproductive Health
  • Women's Health
  • Tobacco Control Research

Background:

  • Female sexual dysfunction (FSD) is a prevalent concern affecting women's quality of life.
  • The impact of smoking on female sexual health requires further investigation, particularly in premenopausal populations.

Purpose of the Study:

  • To determine if smoking is a risk factor for FSD in premenopausal women.
  • To examine the relationship between cumulative smoking dose, nicotine dependency, and FSD severity.

Main Methods:

  • The study included 900 sexually active premenopausal women.
  • Female sexual function was assessed using the Female Sexual Function Index (FSFI) questionnaire.
  • Participants were categorized by smoking status (never/former vs. current smokers) and nicotine dependency levels.

Main Results:

  • The frequency of FSD was significantly higher in current smokers (55.1%) compared to never/former smokers.
  • Increased cumulative smoking dose (pack-years) correlated with lower total FSFI scores (r=-0.278, P<0.05).
  • Smokers with moderate to heavy nicotine dependency exhibited significantly lower FSFI scores than lightly dependent smokers.

Conclusions:

  • Current smoking is an independent risk factor for FSD in premenopausal women.
  • Cumulative smoking dose and nicotine dependency levels are associated with an increased risk and severity of FSD.