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Updated: Apr 6, 2026

Methods to Classify Cytoplasmic Foci as Mammalian Stress Granules
Published on: May 12, 2017
Data in support of 5'AMP-activated protein kinase alpha regulates stress granule biogenesis
Hicham Mahboubi1, Ramla Barisé1, Ursula Stochaj1
1Department of Physiology, McGill University, Montréal, Canada.
Abstract:
This data article contains insights into the regulation of cytoplasmic stress granules (SGs) by 5'-AMP-activated kinase (AMPK). Our results verify the specific association of AMPK-α2, but not AMPK-α1, with SGs. We also provide validation data for the isoform-specific recruitment of the AMPK-α subunit to SGs using (i) different antibodies and (ii) a distinct cellular model system. In addition, we assess the SG association of the regulatory AMPK β- and γ-subunits. The interpretation of these data and further extensive insights into the regulation of SG biogenesis by AMPK can be found in "5'AMP-activated protein kinase alpha regulates stress granule biogenesis" [1].
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