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An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
A Single-Center Multidisciplinary Initiative to Reduce Catheter-Associated Urinary Tract Infection Rates: Quality and
Tori Sutherland1, Jennifer Beloff, Casey McGrath
1Author Affiliations: Department of Anesthesia, Critical Care and Pain Medicine (Sutherland), Beth Israel Deaconess Hospital, Boston, Massachusetts; Department of Quality and Safety (Mss Beloff and McGrath, and Drs Pimentel, Kachalia, and Bates), Brigham and Women's Hospital, Boston, Massachusetts; Division of General Medicine (Ms Liu, and Drs Bates and Kachalia), Brigham and Women's Hospital, Boston, Massachusetts; and Department of Anesthesiology, Perioperative and Pain Medicine (Drs Urman and Pimentel), Brigham and Women's Hospital, Boston, Massachusetts.
Insights
Implementing a low-cost catheter-associated urinary tract infection (CAUTI) reduction program significantly decreased infection rates and saved costs. Sustained focus on interventions is key to maintaining lower CAUTI rates.
Area of Science:
- Healthcare-associated infections
- Patient safety
- Hospital administration
Background:
- Catheter-associated urinary tract infection (CAUTI) is a significant patient safety concern, causing over 449,000 infections annually in the US.
- The estimated annual cost of CAUTI ranges from $115 million to $1.82 billion.
Purpose of the Study:
- To assess the financial impact of a low-cost CAUTI reduction program on hospital direct costs over four years.
- To evaluate the effectiveness of specific interventions in reducing CAUTI rates.
Main Methods:
- Internal revenue analysis with sensitivity analysis over four years.
- Interventions included a multidisciplinary task force, data collection, staff education, and electronic order sets with decision support.
Main Results:
- Infection rates per 1000 catheter days dropped from 5.4 to 1.5 initially, rising to 4.6 before decreasing to 2.2 after further interventions.
- Initial cost savings were $4501 per 1000 catheter days (±20%).
Conclusions:
- Provider education and electronic prompts reduced catheter use and infection rates.
- A decline in intervention focus led to increased CAUTI rates, highlighting the need for sustained efforts.
- Further interventions demonstrated the reversibility of upward trends in infection rates.
Introduction:
Catheter-associated urinary tract infection (CAUTI) is an important patient safety issue that is responsible for an estimated 449334 annual infections, with an average direct cost of $790-$1200 per infection. In total, the cost associated with CAUTI is estimated to be $115 million to $1.82 billion annually.
Methods:
We conducted an internal revenue analysis with a standard sensitivity analysis to assess the impact of a low-cost CAUTI reduction program on direct costs to the hospital over four years. The interventions included the formation of a multidisciplinary CAUTI reduction task force, formal data collection in all ICUs, staff education, and new electronic order sets with decision support.
Results:
During the initial intervention period, the infection rate per 1000 catheter days decreased from 5.4 to 1.5. In the second year of the program, the infection rate increased to 4.6. After additional interventions were launched, infection rates decreased to 2.2. Cost savings per 1000 catheter days (±20%) during the initial intervention were $4501 ($3600-$5401).
Discussion:
Our intervention demonstrated that provider education and electronic documentation prompts were followed by a significant decrease in catheter utilization, that in turn was followed by lower infection rates. Decreased emphasis on intervention goals were followed by an increase in CAUTI rates. Our subsequent interventions suggest that upward trends may be reversible.
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