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An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
A Single-Center Multidisciplinary Initiative to Reduce Catheter-Associated Urinary Tract Infection Rates: Quality and
Tori Sutherland1, Jennifer Beloff, Casey McGrath
1Author Affiliations: Department of Anesthesia, Critical Care and Pain Medicine (Sutherland), Beth Israel Deaconess Hospital, Boston, Massachusetts; Department of Quality and Safety (Mss Beloff and McGrath, and Drs Pimentel, Kachalia, and Bates), Brigham and Women's Hospital, Boston, Massachusetts; Division of General Medicine (Ms Liu, and Drs Bates and Kachalia), Brigham and Women's Hospital, Boston, Massachusetts; and Department of Anesthesiology, Perioperative and Pain Medicine (Drs Urman and Pimentel), Brigham and Women's Hospital, Boston, Massachusetts.
Implementing a low-cost catheter-associated urinary tract infection (CAUTI) reduction program significantly decreased infection rates and saved costs. Sustained focus on interventions is key to maintaining lower CAUTI rates.
Area of Science:
- Healthcare-associated infections
- Patient safety
- Hospital administration
Background:
- Catheter-associated urinary tract infection (CAUTI) is a significant patient safety concern, causing over 449,000 infections annually in the US.
- The estimated annual cost of CAUTI ranges from $115 million to $1.82 billion.
Purpose of the Study:
- To assess the financial impact of a low-cost CAUTI reduction program on hospital direct costs over four years.
- To evaluate the effectiveness of specific interventions in reducing CAUTI rates.
Main Methods:
- Internal revenue analysis with sensitivity analysis over four years.
- Interventions included a multidisciplinary task force, data collection, staff education, and electronic order sets with decision support.
Main Results:
- Infection rates per 1000 catheter days dropped from 5.4 to 1.5 initially, rising to 4.6 before decreasing to 2.2 after further interventions.
- Initial cost savings were $4501 per 1000 catheter days (±20%).
Conclusions:
- Provider education and electronic prompts reduced catheter use and infection rates.
- A decline in intervention focus led to increased CAUTI rates, highlighting the need for sustained efforts.
- Further interventions demonstrated the reversibility of upward trends in infection rates.
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