Related Experiment Video
Updated: Apr 6, 2026

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
Multisystem Effects of Hypertensive Disorders of Pregnancy: A Comprehensive Review
Patricia M Witcher1, Bonnie Flood Chez, Suzanne McMurtry Baird
1Labor and Delivery and High Risk Perinatal Nursing, Women's Services, Northside Hospital, Atlanta, Georgia (Ms Witcher); Nursing Education Resources, Tampa, Florida (Ms Chez); and Clinical Concepts in Obstetrics, Inc, Brentwood, Texas, and Adjunct Faculty, Vanderbilt University School of Nursing, Nashville, Tennessee (Dr Baird).
Insights
Hypertension during pregnancy poses risks to mothers and babies, potentially leading to long-term health issues. Early detection and management of hypertensive disorders are crucial for better outcomes.
Area of Science:
- Obstetrics and Gynecology
- Cardiology
- Neonatology
Background:
- Hypertension during pregnancy presents significant risks for both maternal and fetal well-being.
- These risks extend beyond the immediate postpartum and postnatal periods, impacting long-term health.
- Preterm birth, often necessitated by hypertensive disorders, contributes to neonatal morbidity.
Purpose of the Study:
- To provide a comprehensive review of the multisystem effects of hypertensive disorders in pregnancy.
- To elucidate the underlying pathophysiology of these conditions.
- To support the importance of prompt identification and management of acute hypertensive complications.
Main Methods:
- Literature review of multisystem effects.
- Analysis of pathophysiology of hypertensive disorders.
- Synthesis of evidence supporting timely intervention.
Main Results:
- Hypertensive disorders affect multiple maternal and fetal systems.
- Understanding pathophysiology aids in predicting and managing complications.
- Prompt management of acute complications is vital.
Conclusions:
- Hypertension in pregnancy requires vigilant monitoring and management.
- Comprehensive understanding of its effects is key to mitigating adverse outcomes.
- Early intervention strategies are essential for improving maternal and neonatal health.
Abstract:
Hypertension predisposes the woman and fetus to adverse outcomes during the pregnancy and postpartum. The risk for maternal complications and neonatal morbidity associated with the necessity of preterm birth extends beyond the postpartum and postnatal period. A comprehensive review of the multisystem effects of hypertensive disorders and underlying pathophysiology is provided to support the role of prompt identification of and management of acute complications of hypertension.
More Related Videos
Related Concept Videos
Hypertension II: Pathophysiology
Hormonal Regulation
Hypertension III: Clinical Manifestations and Diagnostic Studies
Disorders of the Autonomic Nervous System
Raynaud's disease, also known as Raynaud's...
Hypertension and Regulation of Blood Pressure
Hypertension V: Nursing Management

