Related Experiment Video
Updated: Apr 6, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Flavonoids, Breast Cancer Chemopreventive and/or Chemotherapeutic Agents
Chantal Beatrice Magne Nde1, Stephane Zingue, Evelyn Winter
1Hudson Institute of Medical Research, 27-31 Wright Street, Clayton, VIC 3168, Melbourne, Australia. chantal.nde@hudson.org.au.
Abstract:
Flavonoids are secondary metabolites abundantly present in commonly consumed fruits and vegetables. They possess diverse properties such as anti-inflammatory, anti-oxidant and anti-cancer. Epidemiologic studies suggest that an enrich flavonoids diet is linked to a decreased risk of breast cancer. These protective properties are due to the alteration of numerous signalling pathways involved in cancer-related phenomena such as inflammation and proliferation. Human clinical trials examining the effect of supplementation of some flavonoids on disease prevention have been conducted. There is no natural flavonoid that has been approved for the treatment of breast cancer. However, natural flavonoids served as lead compounds in the synthesis of cancer chemopreventive and/or therapeutic agents.
More Related Videos
Related Concept Videos
Cancer Prevention
Some...
Cancer Prevention
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase
Inhibition of Cdk Activity
Targeted Cancer Therapies
There are several types of targeted therapies against...

