Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

1.1K
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
1.1K
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

992
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
992
The Pituitary Gland01:17

The Pituitary Gland

15.5K
The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
15.5K
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

1.1K
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
1.1K
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

1.2K
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
1.2K
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

327
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
327

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Macroprolactinemia as a diagnostic pitfall in hyperprolactinemia: a systematic review and quantitative synthesis.

The Journal of clinical endocrinology and metabolism·2026
Same author

The hook effect in macroprolactinomas: tumor size thresholds, prolactin patterns, and clinical consequences - a systematic review.

Pituitary·2026
Same author

Bringing a mobile multidisciplinary clinic to the bedside in a regional dialysis center for patients with diabetes: Responding to our patients' needs.

Irish journal of medical science·2026
Same author

Prolactinoma localization by inferior petrosal sinus sampling: illustrative case.

Journal of neurosurgery. Case lessons·2026
Same author

Real-world diagnostic performance of the macimorelin stimulation test in the diagnosis of adult growth hormone deficiency.

Pituitary·2026
Same author

Which bot is best? Accuracy and readability of generative artificial intelligence assistant responses on adrenal nodules.

American journal of surgery·2026

Related Experiment Video

Updated: Apr 6, 2026

Induction of Experimental Autoimmune Hypophysitis in SJL Mice
10:38

Induction of Experimental Autoimmune Hypophysitis in SJL Mice

Published on: December 17, 2010

12.0K

Lymphocytic infundibulo-neurohypophysitis: a clinical overview.

Philip C Johnston1,2, Luen S Chew3, Amir H Hamrahian3,4

  • 1Department of Endocrinology, Diabetes and Metabolism, Cleveland Clinic Foundation, 9500 Euclid Avenue Desk F20, Cleveland, OH, 44195, USA. pcjohnston@doctors.org.uk.

Endocrine
|July 30, 2015
PubMed
Summary

Lymphocytic infundibulo-neurohypophysitis, an autoimmune inflammatory disorder, commonly causes central diabetes insipidus. Radiological imaging aids diagnosis, complementing histological confirmation.

Keywords:
Anterior and posterior pituitary functionCentral diabetes insipidusLymphocytic infundibulo-neurohypophysitisPituitary gland

More Related Videos

Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
10:52

Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis

Published on: December 17, 2010

15.2K
Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
08:56

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies

Published on: October 7, 2021

3.6K

Related Experiment Videos

Last Updated: Apr 6, 2026

Induction of Experimental Autoimmune Hypophysitis in SJL Mice
10:38

Induction of Experimental Autoimmune Hypophysitis in SJL Mice

Published on: December 17, 2010

12.0K
Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
10:52

Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis

Published on: December 17, 2010

15.2K
Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
08:56

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies

Published on: October 7, 2021

3.6K

Area of Science:

  • Endocrinology
  • Neuroimmunology
  • Pathology

Background:

  • Lymphocytic infundibulo-neurohypophysitis is a rare autoimmune inflammatory condition.
  • It specifically targets the posterior pituitary (neurohypophysis) and pituitary stalk (infundibulum).
  • Central diabetes insipidus is the most frequent clinical manifestation.

Purpose of the Study:

  • To provide a comprehensive overview of lymphocytic infundibulo-neurohypophysitis.
  • To discuss the pathophysiology, diagnostic investigations, management strategies, and patient outcomes.
  • To highlight the role of radiological imaging in diagnosis.

Main Methods:

  • Literature review of lymphocytic infundibulo-neurohypophysitis.
  • Analysis of diagnostic approaches including imaging and histology.
  • Summary of current management and outcome data.

Main Results:

  • The condition is characterized by inflammation affecting the infundibulum and neurohypophysis.
  • Central diabetes insipidus is a hallmark symptom.
  • While pituitary biopsy provides definitive diagnosis, imaging is crucial for early detection.

Conclusions:

  • Lymphocytic infundibulo-neurohypophysitis requires a multi-faceted diagnostic approach.
  • Early recognition and management are key to improving patient outcomes.
  • Further research into its autoimmune basis and therapeutic interventions is warranted.