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Coffee consumption and risk of hypertension in the Polish arm of the HAPIEE cohort study
G Grosso1,2, U Stepaniak2, M Polak2
1Integrated Cancer Registry of Catania-Messina-Siracusa-Enna, Catania, Italy.
Insights
Drinking 3-4 cups of coffee daily may lower hypertension risk, particularly in non-smokers. This association between coffee consumption and blood pressure (BP) incidence is linked to smoking status, with benefits observed in both men and women.
Area of Science:
- Cardiovascular epidemiology
- Nutritional science
- Public health
Background:
- Previous research on coffee consumption and blood pressure (BP) has yielded inconsistent results.
- Understanding the relationship between coffee intake and hypertension risk is crucial for public health guidelines.
Purpose of the Study:
- To investigate the association between coffee consumption and the risk of developing hypertension.
- To clarify the role of confounding factors, such as smoking and gender, in this relationship.
Main Methods:
- A longitudinal study of 2725 participants from the Polish arm of the HAPIEE project.
- Data collected on coffee consumption, BP, and antihypertensive medication use.
- Multivariate logistic regression analyses were used to calculate odds ratios (ORs) and 95% confidence intervals (CIs), with stratification for confounding factors.
Main Results:
- Coffee consumption was associated with decreased age, smoking status, and total energy intake.
- Individuals consuming 3-4 cups of coffee per day showed a significantly lower risk of developing hypertension compared to those drinking less than one cup.
- This protective effect was most pronounced in non-smokers of both sexes, with significant ORs observed for men (0.41) and women (0.54).
- Consuming more than 4 cups of coffee daily did not show a significant association with increased hypertension risk.
Conclusions:
- The relationship between coffee consumption and hypertension incidence is significantly influenced by smoking status.
- Moderate coffee consumption (3-4 cups/day) appears to reduce hypertension risk in non-smoking men and women.
Background/Objectives:
Coffee consumption has been hypothesized to be associated with blood pressure (BP), but previous findings are not homogeneous. The aim of this study was to evaluate the association between coffee consumption and the risk of developing hypertension.
Subjects/Methods:
Data on coffee consumption, BP and use of anti-hypertensive medicament were derived from 2725 participants of the Polish arm of the HAPIEE project (Health, Alcohol and Psychosocial factors In Eastern Europe) who were free of hypertension at baseline and followed up for an average of 5 years. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated by multivariate logistic regression analyses and stratified for potential confounding factors.
Results:
Coffee consumption was related to decreased age, smoking status and total energy intake. Compared with persons who drink <1 cup coffee per day, systolic BP was significantly associated with coffee consumption and the risk of hypertension was lower for individuals consuming 3-4 cups per day. Despite the analysis stratified by gender showed that the protective effect of coffee consumption on hypertension was significant only in women, the analysis after stratification by smoking status revealed a decreased risk of hypertension in non-smokers drinking 3-4 cups of coffee per day in both sexes (OR 0.41, 95% CI: 0.21, 0.79 for men and OR 0.54, 95% CI: 0.29, 0.99 for women). Upper category coffee consumption (>4 cups per day) was not related to significant increased risk of hypertension.
Conclusions:
Relation between coffee consumption and incidence of hypertension was related to smoking status. Consumption of 3-4 cups of coffee per day decreased the risk of hypertension in non-smoking men and women only.
Related Concept Videos
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Physiological Factors:
Hypertension and Regulation of Blood Pressure
Hypertension I: Introduction
Hypertension II: Pathophysiology
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension IV: Drug Therapy and Lifestyle Modifications