Related Experiment Video
Updated: Apr 6, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
A new potent immunosuppressive isoflavanonol from Campylotropis hirtella
Bixia Xuan1, Xing Du1, Xiaoping Li1
1a School of Pharmacy , Shanghai University of Traditional Chinese Medicine , Shanghai , China.
Abstract:
Four new flavonoids were isolated from Campylotropis hirtella and these are a chromone and a 2H-chromene, an isoflavone and an isoflavanonol. The structures of these compounds were elucidated by extensive spectroscopic measurements. All of the compounds were assessed for immunosuppressive activity. Compound 4 showed very strong T lymphocyte suppression activity (IC50: 0.13 μM) and potent B lymphocyte suppression activity (IC50: 0.26 μM). Due to its potent immunosuppressive activity and lower cytotoxicity, further structure-activity studies will be pursued on this compound.
More Related Videos
Related Concept Videos
Plant Hormones
Plant Hormones
Introduction to Plant Diversity
Seedless Vascular Plants
Cancer Prevention
Some...
Antifungal Agents

