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Incidence and mortality of ischemic stroke subtypes in Joinville, Brazil: a population-based study

Marcos C Lange1, Norberto L Cabral2, Carla H C Moro2

  • 1Divisão de Neurologia, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.

Arquivos De Neuro-Psiquiatria
|July 30, 2015
PubMed

Insights

This study measured ischemic stroke (IS) incidence and mortality in Joinville, Brazil. Findings show subtype rates are comparable globally, emphasizing the need to manage atherosclerotic risk factors.

Area of Science:

  • Neurology
  • Epidemiology
  • Public Health

Background:

  • Ischemic stroke (IS) is a major cause of disability and death worldwide.
  • Understanding the incidence and mortality of specific IS subtypes is crucial for targeted prevention and treatment strategies.
  • Joinville, Brazil, provides a specific population context for epidemiological stroke research.

Purpose of the Study:

  • To determine the age-adjusted incidence and one-year mortality rates of ischemic stroke subtypes in Joinville, Brazil.
  • To classify IS subtypes using the TOAST criteria.
  • To provide epidemiological data on stroke in a Brazilian population.

Main Methods:

  • A population-based study identified all first-ever IS patients in Joinville between January 2005 and December 2006.
  • Ischemic stroke subtypes were classified according to the TOAST criteria.
  • Patients were followed for one year post-stroke to ascertain mortality.

Main Results:

  • Age-adjusted incidence per 100,000 inhabitants: Large-artery atherosclerosis (LAA) 26, Cardioembolic (CE) 17, Small vessel occlusion (SVO) 29, Other determined etiology (OTH) 2, Undetermined etiology (UND) 30.
  • One-year mortality rates per 100,000 inhabitants: LAA 5, CE 6, SVO 1, OTH 0.2, UND 9.
  • Incidence rates for LAA, CE, SVO, and UND subtypes were observed.

Conclusions:

  • The incidence rates of ischemic stroke subtypes in Joinville are comparable to those reported in other international populations.
  • The findings underscore the critical importance of enhanced detection and management of atherosclerotic risk factors to reduce stroke burden.
  • Further research into stroke etiology and prevention in diverse populations is warranted.
Abstract

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