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Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

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Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
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X-ray Imaging01:24

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German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
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Different notations are used to represent the three-dimensional structure of molecules on two-dimensional surfaces. One of the most commonly used representations is the dash-wedge formula. The dashed wedges, solid wedges, and the plane lines indicate the groups situated behind the plane, coming out of the plane, and in the plane, respectively.
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Fischer Projections02:18

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Learning to draw Fischer projections of molecules and understanding their relevance plays a crucial role in the visual depiction of organic molecules. A Fischer projection is a two-dimensional projection on a planar surface to simplify the three-dimensional wedge–dash representation of molecules. This is especially helpful in the case of molecules with multiple chiral centers that can be difficult to draw. Here, all the bonds of interest are represented as horizontal or vertical lines. While...
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Osmosis00:47

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Approximately 60% to 95% of the weight of living organisms is attributed to water. Therefore, maintaining appropriate water balance within cells is of paramount importance. Osmosis is the movement of water across a semipermeable membrane, such as a cell’s plasma membrane. In living organisms, water plays a crucial role as a solvent—a molecule that dissolves other molecules.
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It is far more common for collisions to occur in two dimensions; that is, the initial velocity vectors are neither parallel nor antiparallel to each other. Let's see what complications arise from this. The first idea is that momentum is a vector. Like all vectors, it can be expressed as a sum of perpendicular components (usually, though not always, an x-component and a y-component, and a z-component if necessary). Thus, when the statement of conservation of momentum is written for a...
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Updated: Apr 6, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
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Publishing and sharing multi-dimensional image data with OMERO.

Jean-Marie Burel1, Sébastien Besson1, Colin Blackburn1

  • 1Centre for Gene Regulation & Expression, University of Dundee, Dundee, Scotland, UK.

Mammalian Genome : Official Journal of the International Mammalian Genome Society
|July 31, 2015
PubMed
Summary
This summary is machine-generated.

The OMERO platform securely manages and shares large imaging datasets for life sciences research. It offers granular user permissions for private, collaborative, or public data access, enhancing scientific collaboration.

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Area of Science:

  • Biomedical imaging
  • Life sciences research
  • Data management

Background:

  • Imaging data are crucial for understanding molecular and structural dynamics in biological systems.
  • Biomedical datasets vary greatly in size, from megabytes to terabytes.
  • Effective management and sharing of these large datasets are essential for scientific progress.

Purpose of the Study:

  • To introduce the OMERO image data management platform.
  • To highlight OMERO's capabilities for secure and flexible sharing of imaging data.
  • To demonstrate how OMERO facilitates collaboration and data accessibility in research.

Main Methods:

  • Utilizing the OMERO platform for image data storage and organization.
  • Implementing OMERO's permission system to control data access.
  • Leveraging OMERO Groups for defining user membership and access rights.
  • Exploring OMERO's features for private, shared, and public data dissemination.

Main Results:

  • OMERO enables secure sharing of image datasets with defined permission levels.
  • Users can manage access through private data, shared collections, or public URLs.
  • The platform supports various collaborative scenarios, including lab sharing, group analysis, and teaching.

Conclusions:

  • OMERO provides a robust solution for managing and sharing large-scale biomedical imaging data.
  • Its flexible permission system enhances data security and facilitates collaborative research.
  • OMERO is an open-source platform contributing to the advancement of life sciences research.